decompTumor2Sig
Bioc currentDecomposition of individual tumors into mutational signatures by signature refitting
v2.28.0
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software
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GPL-2
Release Lineage
Entered 3.9 · May 3, 2019
Current · Requires R 4.6
1.0
In 15 of 49 releases
3.23
Description
Uses quadratic programming for signature refitting, i.e., to decompose the mutation catalog from an individual tumor sample into a set of given mutational signatures (either Alexandrov-model signatures or Shiraishi-model signatures), computing weights that reflect the contributions of the signatures to the mutation load of the tumor.
Code
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Topics
Depended on by (1)
Bioconductor (1)
People
- Rosario M. Piro author maintainer
- Sandra Krueger contributor