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UMI4Cats

Bioc current

UMI4Cats: Processing, analysis and visualization of UMI-4C chromatin contact data

v1.22.0 · software · Artistic-2.0
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Release Lineage

Entered 3.12 · Oct 28, 2020

Current · Requires R 4.6

1.0 In 12 of 49 releases 3.23

Description

UMI-4C is a technique that allows characterization of 3D chromatin interactions with a bait of interest, taking advantage of a sonication step to produce unique molecular identifiers (UMIs) that help remove duplication bias, thus allowing a better differential comparsion of chromatin interactions between conditions. This package allows processing of UMI-4C data, starting from FastQ files provided by the sequencing facility. It provides two statistical methods for detecting differential contacts and includes a visualization function to plot integrated information from a UMI-4C assay.

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Topics

Software › WorkflowStep › QualityControl
Software › WorkflowStep › Preprocessing
Software › WorkflowStep › Alignment
Software › WorkflowStep › Normalization
Software › WorkflowStep › Visualization
Software › Technology › Sequencing
Software › BiologicalQuestion › Coverage

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