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SpaNorm

Bioc current

Spatially-aware normalisation for spatial transcriptomics data

v1.6.0 · software · GPL (>= 3)
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Release Lineage

Entered 3.20 · Oct 30, 2024

Current · Requires R 4.6

1.0 In 4 of 49 releases 3.23

Description

This package implements the spatially aware library size normalisation algorithm, SpaNorm. SpaNorm normalises out library size effects while retaining biology through the modelling of smooth functions for each effect. Normalisation is performed in a gene- and cell-/spot- specific manner, yielding library size adjusted data.

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Topics

Software
Software › AssayDomain › GeneExpression
Software › ResearchField › Transcriptomics
Software › Technology › Spatial
Software › ResearchField › CellBiology

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