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Coralysis

Bioc current

Coralysis sensitive identification of imbalanced cell types and states in single-cell data via multi-level integration

v1.2.0 · software · GPL-3

Release Lineage

Entered 3.22 · Oct 30, 2025

Current · Requires R 4.6

1.0 In 2 of 49 releases 3.23

Description

Coralysis is an R package featuring a multi-level integration algorithm for sensitive integration, reference-mapping, and cell-state identification in single-cell data. The multi-level integration algorithm is inspired by the process of assembling a puzzle - where one begins by grouping pieces based on low-to high-level features, such as color and shading, before looking into shape and patterns. This approach progressively blends the batch effects and separates cell types across multiple rounds of divisive clustering.

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