zinbwave

Description

Implements a general and flexible zero-inflated negative binomial model that can be used to provide a low-dimensional representations of single-cell RNA-seq data. The model accounts for zero inflation (dropouts), over-dispersion, and the count nature of the data. The model also accounts for the difference in library sizes and optionally for batch effects and/or other covariates, avoiding the need for pre-normalize the data.

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Code

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Topics

Depended on by (7)

People

• Davide Risso author maintainer cph
• Clara Bagatin author
• Svetlana Gribkova author
• Fanny Perraudeau author
• Jean-Philippe Vert author