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CleanUpRNAseq

Bioc current

Detect and Correct Genomic DNA Contamination in RNA-seq Data

v1.6.0 · software · GPL-3
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Release Lineage

Entered 3.20 · Oct 30, 2024

Current · Requires R 4.6

1.0 In 4 of 49 releases 3.23

Description

RNA-seq data generated by some library preparation methods, such as rRNA-depletion-based method and the SMART-seq method, might be contaminated by genomic DNA (gDNA), if DNase I disgestion is not performed properly during RNA preparation. CleanUpRNAseq is developed to check if RNA-seq data is suffered from gDNA contamination. If so, it can perform correction for gDNA contamination and reduce false discovery rate of differentially expressed genes.

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Topics

Software › WorkflowStep › QualityControl
Software › Technology › Sequencing
Software › AssayDomain › GeneExpression

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