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vmrseq

Bioc current

Probabilistic Modeling of Single-cell Methylation Heterogeneity

v1.4.0 · software · MIT + file LICENSE
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Release Lineage

Entered 3.21 · Apr 16, 2025

Current · Requires R 4.6

1.0 In 3 of 49 releases 3.23

Description

High-throughput single-cell measurements of DNA methylation allows studying inter-cellular epigenetic heterogeneity, but this task faces the challenges of sparsity and noise. We present vmrseq, a statistical method that overcomes these challenges and identifies variably methylated regions accurately and robustly.

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Topics

Software
Software › ResearchField › Immunology › ImmunoOncology
Software › AssayDomain › DNAMethylation
Software › ResearchField › Epigenetics
Software › Technology › SingleCell
Software › Technology › Sequencing
Software › Technology › Sequencing › WholeGenome

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