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normr

Bioc current

Normalization and difference calling in ChIP-seq data

v1.38.1 · software · GPL-2
View on Bioconductor ↗ Source ↗

Release Lineage

Entered 3.4 · Oct 18, 2016

Current · Requires R 4.6

1.0 In 20 of 49 releases 3.23

Description

Robust normalization and difference calling procedures for ChIP-seq and alike data. Read counts are modeled jointly as a binomial mixture model with a user-specified number of components. A fitted background estimate accounts for the effect of enrichment in certain regions and, therefore, represents an appropriate null hypothesis. This robust background is used to identify significantly enriched or depleted regions.

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Topics

Software › StatisticalMethod › Bayesian
Software › BiologicalQuestion › DifferentialPeakCalling
Software › StatisticalMethod › Classification
Software › Infrastructure › DataImport
Software › Technology › Sequencing › ChIPSeq
Software › Technology › Sequencing › RIPSeq
Software › ResearchField › FunctionalGenomics
Software › ResearchField › Genetics
Software › WorkflowStep › MultipleComparison
Software › WorkflowStep › Normalization
Software › BiologicalQuestion › PeakDetection
Software › WorkflowStep › Preprocessing
Software › WorkflowStep › Alignment

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