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CDI

Bioc current

Clustering Deviation Index (CDI)

v1.10.0 · software · GPL-3 + file LICENSE

Release Lineage

Entered 3.18 · Oct 25, 2023

Current · Requires R 4.6

1.0 In 6 of 49 releases 3.23

Description

Single-cell RNA-sequencing (scRNA-seq) is widely used to explore cellular variation. The analysis of scRNA-seq data often starts from clustering cells into subpopulations. This initial step has a high impact on downstream analyses, and hence it is important to be accurate. However, there have not been unsupervised metric designed for scRNA-seq to evaluate clustering performance. Hence, we propose clustering deviation index (CDI), an unsupervised metric based on the modeling of scRNA-seq UMI counts to evaluate clustering of cells.

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