simFastBOIN

1.3.2

Fast Bayesian Optimal Interval Design for Phase I Dose-Finding Trials

0packages depend

1.3Kdownloads / year

80.4%test coverage

13/13checks pass

Overview

About

Maintained by Gosuke HommaFirst published 2025-12-171 releasesCRAN page ↗GitHub ↗

Conducting Bayesian Optimal Interval (BOIN) design for phase I dose-finding trials. 'simFastBOIN' provides functions for pre-computing decision tables, conducting trial simulations, and evaluating operating characteristics. The package uses vectorized operations and the Iso::pava() function for isotonic regression to achieve efficient performance while maintaining full compatibility with BOIN methodology. Version 1.3.2 adds p_saf and p_tox parameters for customizable safety and toxicity thresholds. Version 1.3.1 fixes Date field. Version 1.2.1 adds comprehensive 'roxygen2' documentation and enhanced print formatting with flexible table output options. Version 1.2.0 integrated C-based PAVA for isotonic regression. Version 1.1.0 introduced conservative MTD selection (boundMTD) and flexible early stopping rules (n_earlystop_rule). Methods are described in Liu and Yuan (2015) doi:10.1111/rssc.12089.

Install

R (CRAN)pak (dev)Ubuntu (r2u)openSUSE (OBS)

install.packages("simFastBOIN", repos = "https://cloud.r-project.org/")

Installs the current CRAN release. Prebuilt binaries on Windows and macOS.

if (!requireNamespace("pak", quietly = TRUE))
  install.packages("pak", repos = "https://cloud.r-project.org/")
pak::pak("gosukehommaEX/simFastBOIN")

Development version from gosukehommaEX/simFastBOIN. Installs pak first if it is not already available.

Release

# enable cranapt (r2u) if it is not already set up, then install
grep -rqs r2u.stat.illinois.edu /etc/apt/sources.list /etc/apt/sources.list.d/ \
  || curl -fsSL https://raw.githubusercontent.com/eddelbuettel/r2u/master/inst/scripts/add_cranapt_noble.sh | sudo bash
sudo apt install -y r-cran-simfastboin

Fast Ubuntu binaries via r2u (no compilation). The cranapt setup runs once and is skipped when it is already enabled.

bspm (used by r2u) also needs make: sudo apt install make

# add the autoCRAN OBS repo (Tumbleweed) if it is missing, then install
zypper -q lr | grep -qi autoCRAN \
  || sudo zypper addrepo https://download.opensuse.org/repositories/devel:/languages:/R:/autoCRAN/openSUSE_Tumbleweed/devel:languages:R:autoCRAN.repo
sudo zypper install -y R-simFastBOIN

RPMs auto-built from CRAN on openSUSE OBS (Tumbleweed).

Health

CRAN checks

13OK

Slowest check: 1.7 min · r-oldrel-windows-x86_64

Check history

OK2026-06-08
13 OK · 0 NOTE · 0 WARNING · 0 ERROR · 0 FAILURE
WARNING2026-06-07
12 OK · 0 NOTE · 1 WARNING · 0 ERROR · 0 FAILURE
OK2026-03-10
14 OK · 0 NOTE · 0 WARNING · 0 ERROR · 0 FAILURE

Documentation

Documentation signals are not tracked yet for this package.

Downloads

1.3K

CRAN downloads in the past year

Rank #23,786 · ~4/day · ~107/mo

simFastBOIN Releases R versions

Daily download trend is not available in this view yet.

11630 days

40590 days

1.3K1 year

Compare downloads with other packages →

Also on39 r2u31 autocran

Repository

GitHub ↗ gosukehommaex/simfastboin

1Stars

0Forks

0Open issues

0Open PRs

0Releases

90Commits

1Contributors

clinical-trialsdose-findingoncology-trialsphase1

90 commits · Last activity 2025-12-11 · 0% stars, 30d

Repository practices

Upstream repositoryBeta

4 development-tooling and community-health practices detected across 3 families in the upstream repository

Checks run against github.com/gosukehommaex/simfastboin on 2026-07-19.

Continuous integration (1)

GitHub Actions

CRAN release process (2)

cran-comments.mdCRAN-SUBMISSION

Lint, format, editor (1)

RStudio project

How this is detected·Detection ruleset v1 (2026-07-18)

Dependencies

Declared dependencies

5 external dependencies (excludes base and recommended)

Depends (0)

none

Imports (4)

knitr kableExtra Isostats

LinkingTo (0)

none

Suggests (2)

testthat rmarkdown

Enhances (0)

none

Dependency license breakdown →

Reverse dependencies

0direct

0indirect

Nothing depends on this yet.

Code & Tests

People & History

People (1)

Maintainer (1)

Gosuke Homma

Author, Maintainer

Authors (1)

Gosuke Homma

Author, Maintainer

Package Timeline

1 release. R releases are shown for context.

R
R 4.6.0 released · 2026-04-24
1.3.2Latest
2026-03-10 · current release
R
R 4.5.0 released · 2025-04-11

Package metadata

First published: 2025-12-17
Total releases: 1 / 1 yrs
License: MIT + file LICENSE OSI
Download size: 125 KB
Installed size: not tracked yet
With dependencies: not tracked yet

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