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rxode2

Facilities for Simulating from ODE-Based Models

v5.0.1 · Dec 9, 2025 · GPL (>= 3)

Description

Facilities for running simulations from ordinary differential equation ('ODE') models, such as pharmacometrics and other compartmental models. A compilation manager translates the ODE model into C, compiles it, and dynamically loads the object code into R for improved computational efficiency. An event table object facilitates the specification of complex dosing regimens (optional) and sampling schedules. NB: The use of this package requires both C and Fortran compilers, for details on their use with R please see Section 6.3, Appendix A, and Appendix D in the "R Administration and Installation" manual. Also the code is mostly released under GPL. The 'VODE' and 'LSODA' are in the public domain. The information is available in the inst/COPYRIGHTS.

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CRAN Check Status

3 NOTE
11 OK
Show all 14 flavors
Flavor Status
r-devel-linux-x86_64-debian-clang OK
r-devel-linux-x86_64-debian-gcc OK
r-devel-linux-x86_64-fedora-clang OK
r-devel-linux-x86_64-fedora-gcc OK
r-devel-macos-arm64 OK
r-devel-windows-x86_64 OK
r-oldrel-macos-arm64 NOTE
r-oldrel-macos-x86_64 NOTE
r-oldrel-windows-x86_64 NOTE
r-patched-linux-x86_64 OK
r-release-linux-x86_64 OK
r-release-macos-arm64 OK
r-release-macos-x86_64 OK
r-release-windows-x86_64 OK
Check details (14 non-OK)
OK r-devel-linux-x86_64-debian-clang

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OK r-devel-linux-x86_64-debian-gcc

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OK r-devel-linux-x86_64-fedora-clang

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OK r-devel-linux-x86_64-fedora-gcc

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OK r-devel-macos-arm64

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OK r-devel-windows-x86_64

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NOTE r-oldrel-macos-arm64

installed package size

  installed size is 11.1Mb
  sub-directories of 1Mb or more:
    R         2.0Mb
    include   1.3Mb
    libs      5.9Mb
NOTE r-oldrel-macos-x86_64

installed package size

  installed size is 11.8Mb
  sub-directories of 1Mb or more:
    R         2.0Mb
    include   1.3Mb
    libs      6.6Mb
NOTE r-oldrel-windows-x86_64

installed package size

  installed size is  9.3Mb
  sub-directories of 1Mb or more:
    R         1.4Mb
    include   1.3Mb
    libs      4.7Mb
OK r-patched-linux-x86_64

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OK r-release-linux-x86_64

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OK r-release-macos-arm64

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OK r-release-macos-x86_64

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OK r-release-windows-x86_64

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Check History

NOTE 11 OK · 3 NOTE · 0 WARNING · 0 ERROR · 0 FAILURE Mar 9, 2026
NOTE r-oldrel-macos-arm64

installed package size

  installed size is 11.1Mb
  sub-directories of 1Mb or more:
    R         2.0Mb
    include   1.3Mb
    libs      5.9Mb
NOTE r-oldrel-macos-x86_64

installed package size

  installed size is 11.8Mb
  sub-directories of 1Mb or more:
    R         2.0Mb
    include   1.3Mb
    libs      6.6Mb
NOTE r-oldrel-windows-x86_64

installed package size

  installed size is  9.3Mb
  sub-directories of 1Mb or more:
    R         1.4Mb
    include   1.3Mb
    libs      4.7Mb

Reverse Dependencies (20)

Dependency Network

Dependencies Reverse dependencies PreciseSums Rcpp backports cli (>= 2.0.0) checkmate ggplot2 inline lotri (>= 1.0.2) magrittr memoise rex sys dparser rxode2ll data.table (>= 1.12.4) +1 more dependencies babelmixr2 monolix2rx nlmixr2 nlmixr2auto nlmixr2autoinit nlmixr2est nlmixr2extra nlmixr2lib nlmixr2plot nlmixr2rpt nonmem2rx posologyr shinyMixR PKbioanalysis campsis +5 more reverse deps rxode2

Version History

new 5.0.1 Mar 9, 2026