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plmmr

Penalized Linear Mixed Models for Correlated Data

v4.2.3 · Jan 26, 2026 · GPL-3

Description

Fits penalized linear mixed models that correct for unobserved confounding factors. 'plmmr' infers and corrects for the presence of unobserved confounding effects such as population stratification and environmental heterogeneity. It then fits a linear model via penalized maximum likelihood. Originally designed for the multivariate analysis of single nucleotide polymorphisms (SNPs) measured in a genome-wide association study (GWAS), 'plmmr' eliminates the need for subpopulation-specific analyses and post-analysis p-value adjustments. Functions for the appropriate processing of 'PLINK' files are also supplied. For examples, see the package homepage. <https://pbreheny.github.io/plmmr/>.

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CRAN Check Status

1 WARNING
13 OK
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r-devel-linux-x86_64-debian-clang OK
r-devel-linux-x86_64-debian-gcc OK
r-devel-linux-x86_64-fedora-clang OK
r-devel-linux-x86_64-fedora-gcc OK
r-devel-macos-arm64 OK
r-devel-windows-x86_64 OK
r-oldrel-macos-arm64 WARNING
r-oldrel-macos-x86_64 OK
r-oldrel-windows-x86_64 OK
r-patched-linux-x86_64 OK
r-release-linux-x86_64 OK
r-release-macos-arm64 OK
r-release-macos-x86_64 OK
r-release-windows-x86_64 OK
Check details (14 non-OK)
OK r-devel-linux-x86_64-debian-clang

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OK r-devel-linux-x86_64-debian-gcc

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OK r-devel-linux-x86_64-fedora-clang

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OK r-devel-linux-x86_64-fedora-gcc

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OK r-devel-macos-arm64

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OK r-devel-windows-x86_64

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WARNING r-oldrel-macos-arm64

whether package can be installed

Found the following significant warnings:
  Warning: OpenMP is not available, project will be compiled into single-thread code. Use OpenMP-enabled compiler to get benefit of multi-threading. [-W#pragma-messages]8./utilities.h:
  Warning: OpenMP is not available, project will be compiled into single-thread code. Use OpenMP-enabled compiler to get benefit of multi-threading. [-W#pragma-messages]
See ‘/Volumes/Builds/packages/big-sur-arm64/results/4.4/plmmr.Rcheck/00install.out’ for details.
* used C compiler: ‘Apple clang version 14.0.3 (clang-1403.0.22.14.1)’
* used C++ compiler: ‘Apple clang version 14.0.3 (clang-1403.0.22.14.1)’
* used SDK: ‘MacOSX11.3.sdk’
OK r-oldrel-macos-x86_64

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OK r-oldrel-windows-x86_64

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OK r-patched-linux-x86_64

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OK r-release-linux-x86_64

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OK r-release-macos-arm64

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OK r-release-macos-x86_64

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OK r-release-windows-x86_64

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Check History

WARNING 13 OK · 0 NOTE · 1 WARNING · 0 ERROR · 0 FAILURE Mar 9, 2026
WARNING r-oldrel-macos-arm64

whether package can be installed

Found the following significant warnings:
  Warning: OpenMP is not available, project will be compiled into single-thread code. Use OpenMP-enabled compiler to get benefit of multi-threading. [-W#pragma-messages]8./utilities.h:
  Warning: OpenMP is not available, project will be compiled into single-thread code. Use OpenMP-enabled compiler to get benefit of multi-threading. [-W#pragma-messages]
See ‘/Volumes/Builds/packages/big-sur-arm64/results/4.4/plmmr.Rcheck/00install.out’ for details.
* used

Dependency Network

Dependencies Reverse dependencies bigalgebra bigmemory biglasso data.table glmnet Matrix ncvreg plmmr

Version History

new 4.2.3 Mar 9, 2026