pleioh2g

0.1.3

Estimation of Pleiotropic Heritability from Genome-Wide Association Studies (GWAS) Summary Statistics

0packages depend

2.4Kdownloads / year

3.7%test coverage

12/13checks pass

Overview

About

Maintained by Yujie ZhaoFirst published 2025-10-284 releasesCRAN page ↗

Provides tools to compute unbiased pleiotropic heritability estimates of complex diseases from genome-wide association studies (GWAS) summary statistics. We estimate pleiotropic heritability from GWAS summary statistics by estimating the proportion of variance explained from an estimated genetic correlation matrix (Bulik-Sullivan et al. 2015 doi:10.1038/ng.3406) and employing a Monte-Carlo bias correction procedure to account for sampling noise in genetic correlation estimates.

Install

R (CRAN)Ubuntu (r2u)Fedora (COPR)openSUSE (OBS)

install.packages("pleioh2g", repos = "https://cloud.r-project.org/")

Installs the current CRAN release. Prebuilt binaries on Windows and macOS.

Release

# enable cranapt (r2u) if it is not already set up, then install
grep -rqs r2u.stat.illinois.edu /etc/apt/sources.list /etc/apt/sources.list.d/ \
  || curl -fsSL https://raw.githubusercontent.com/eddelbuettel/r2u/master/inst/scripts/add_cranapt_noble.sh | sudo bash
sudo apt install -y r-cran-pleioh2g

Fast Ubuntu binaries via r2u (no compilation). The cranapt setup runs once and is skipped when it is already enabled.

bspm (used by r2u) also needs make: sudo apt install make

# enable the iucar/cran COPR if it is not already present, then install
ls /etc/yum.repos.d/*iucar*cran*.repo >/dev/null 2>&1 \
  || sudo dnf copr enable -y iucar/cran
sudo dnf install -y R-CRAN-pleioh2g

RPMs from the iucar/cran COPR, rebuilt from CRAN.

For install.packages() integration in R, also: sudo dnf install R-CoprManager

# add the autoCRAN OBS repo (Tumbleweed) if it is missing, then install
zypper -q lr | grep -qi autoCRAN \
  || sudo zypper addrepo https://download.opensuse.org/repositories/devel:/languages:/R:/autoCRAN/openSUSE_Tumbleweed/devel:languages:R:autoCRAN.repo
sudo zypper install -y R-pleioh2g

RPMs auto-built from CRAN on openSUSE OBS (Tumbleweed).

Health

CRAN checks

1NOTE12OK

Failing flavors

NOTE r-devel-linux-x86_64-debian-gcc

Slowest check: 1.8 min · r-oldrel-windows-x86_64

Code health

Yes

Tests · ratio 0.03

3.7%

Coverage · measured lines

Dependencies · direct

Check history

NOTE2026-08-01
12 OK · 1 NOTE · 0 WARNING · 0 ERROR · 0 FAILURE
OK2026-06-08
13 OK · 0 NOTE · 0 WARNING · 0 ERROR · 0 FAILURE
ERROR2026-06-07
12 OK · 0 NOTE · 0 WARNING · 1 ERROR · 0 FAILURE
OK2026-03-10
14 OK · 0 NOTE · 0 WARNING · 0 ERROR · 0 FAILURE

Documentation

READMENoVignettesYes · dynamicpkgdown siteNoNEWSNoCode of conductNoContributing guideNo

Examples that run: 70%
Documented parameters: not tracked
Return-value docs: not tracked
References docs: 0%

Downloads

2.4K

CRAN downloads in the past year

Rank #14,849 · ~7/day · ~203/mo

Releases R versions

Daily download trend is not available in this view yet.

19930 days

70190 days

2.4K1 year

Compare downloads with other packages →

Also on106 r2u

Dependencies

Declared dependencies

16 external dependencies (excludes base and recommended)

Depends (1)

R >= 2.10

Imports (14)

data.table dplyrstatsrlang mvtnorm fs arrow checkmate cli gdata glue purrr tibble vroom

LinkingTo (0)

none

Suggests (3)

knitr rmarkdown testthat

Enhances (0)

none

Dependency license breakdown →

Reverse dependencies

0direct

0indirect

Nothing depends on this yet.

Code & Tests

People & History

People (1)

Maintainer (1)

Yujie Zhao

Author, Maintainer

Authors (1)

Yujie Zhao

Author, Maintainer

Package Timeline

4 releases. Pick two to compare their code metrics. R releases are shown for context.

0.1.3Latest
2026-06-09 · current release · diff ↗
R
R 4.6.0 released · 2026-04-24
0.1.2
2026-03-09 · diff ↗
0.1.1
2026-02-19 · diff ↗
0.1.0
2025-10-28
R
R 4.5.0 released · 2025-04-11

Package metadata

First published: 2025-10-28
Total releases: 4 / 1 yrs
License: GPL-3 OSI
Minimum R: ≥ 2.10
Bundled data: 4.4 MB / 5 files
Download size: 4.4 MB
Installed size: not tracked yet
With dependencies: not tracked yet

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