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metasplines

Pool Literature-Based and Individual Participant Data Based Spline Estimates

v0.1.1 · Jan 12, 2026 · GPL (>= 3)

Description

Pooling estimates reported in meta-analyses (literature-based, LB) and estimates based on individual participant data (IPD) is not straight-forward as the details of the LB nonlinear function estimate are not usually reported. This package pools the nonlinear IPD dose-response estimates based on a natural cubic spline from lm or glm with the pointwise LB estimates and their estimated variances. Details will be presented in Härkänen, Tapanainen, Sares-Jäske, Männistö, Kaartinen and Paalanen (2026) "Novel pooling method for nonlinear cohort analysis and meta-analysis estimates: Predicting health outcomes based on climate-friendly diets" Epidemiology <doi:10.1097/EDE.0000000000001932>.

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r-oldrel-windows-x86_64 OK
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r-release-windows-x86_64 OK
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OK 14 OK · 0 NOTE · 0 WARNING · 0 ERROR · 0 FAILURE Mar 9, 2026

Dependency Network

Dependencies Reverse dependencies rlang dplyr tidyr tibble stringr meta optimization metasplines

Version History

new 0.1.1 Mar 9, 2026