metalcor

1.0.0

Meta-Analysis of Correlated Genetic Association Studies

0packages depend

740downloads / year

–test coverage

13/13checks pass

Overview

About

Maintained by Alejandro OchoaFirst published 2026-05-121 releasesCRAN page ↗GitHub ↗

The main function performs meta-analysis of genetic association study summary statistics that may be correlated due to cryptic relatedness or other confounders, generalizing inverse variance weighted methods. The function that estimates the correlation structure is also provided standalone. Another key innovation, the estimation of the correlation parameter from the median product of correlated standard normal variables, is provided, as well as a complete set of functions for their underlying distribution: density, cumulative, quantile, and random deviates. Described in Tu and Ochoa (2025) doi:10.1101/2025.05.10.653279.

Install

R (CRAN)pak (dev)Ubuntu (r2u)Fedora (COPR)openSUSE (OBS)

install.packages("metalcor", repos = "https://cloud.r-project.org/")

Installs the current CRAN release. Prebuilt binaries on Windows and macOS.

if (!requireNamespace("pak", quietly = TRUE))
  install.packages("pak", repos = "https://cloud.r-project.org/")
pak::pak("OchoaLab/metalcor")

Development version from OchoaLab/metalcor. Installs pak first if it is not already available.

Release

# enable cranapt (r2u) if it is not already set up, then install
grep -rqs r2u.stat.illinois.edu /etc/apt/sources.list /etc/apt/sources.list.d/ \
  || curl -fsSL https://raw.githubusercontent.com/eddelbuettel/r2u/master/inst/scripts/add_cranapt_noble.sh | sudo bash
sudo apt install -y r-cran-metalcor

Fast Ubuntu binaries via r2u (no compilation). The cranapt setup runs once and is skipped when it is already enabled.

bspm (used by r2u) also needs make: sudo apt install make

# enable the iucar/cran COPR if it is not already present, then install
ls /etc/yum.repos.d/*iucar*cran*.repo >/dev/null 2>&1 \
  || sudo dnf copr enable -y iucar/cran
sudo dnf install -y R-CRAN-metalcor

RPMs from the iucar/cran COPR, rebuilt from CRAN.

For install.packages() integration in R, also: sudo dnf install R-CoprManager

# add the autoCRAN OBS repo (Tumbleweed) if it is missing, then install
zypper -q lr | grep -qi autoCRAN \
  || sudo zypper addrepo https://download.opensuse.org/repositories/devel:/languages:/R:/autoCRAN/openSUSE_Tumbleweed/devel:languages:R:autoCRAN.repo
sudo zypper install -y R-metalcor

RPMs auto-built from CRAN on openSUSE OBS (Tumbleweed).

Health

CRAN checks

13OK

Slowest check: 2.3 min · r-devel-linux-x86_64-fedora-gcc

Code health

Yes

Tests · ratio 0.34

not tracked

Coverage

100%

Documentation · exports

Yes

Vignettes

Yes

README

Dependencies · direct

Check history

OK2026-05-13
7 OK · 0 NOTE · 0 WARNING · 0 ERROR · 0 FAILURE

Downloads

740

CRAN downloads in the past year

Rank #14,990 · ~2/day · ~62/mo

Releases R versions

Daily download trend is not available in this view yet.

34030 days

74090 days

7401 year

Compare downloads with other packages →

Also on7 r2u6 autocran

Repository

GitHub ↗ ochoalab/metalcor

1Stars

0Forks

0Open issues

0Open PRs

0Releases

License GPL-3.0

Stars over time

2026-05-11 · 12026-07-07 · 1

Dependencies

Declared dependencies

6 external dependencies (excludes base and recommended)

Depends (0)

none

Imports (4)

statsdplyr tibble tidyselect

LinkingTo (0)

none

Suggests (3)

knitr rmarkdown testthat

Enhances (0)

none

Dependency license breakdown →

Reverse dependencies

0direct

0indirect

Nothing depends on this yet.

Code & Tests

Code Composition

R 924 (64%)Rd 295 (20%)Vignettes 227 (16%)

Code characteristics

Cyclomatic complexity: 8.0 median / 19 max
Test cases: 4 / 0.34 per code line
Documented parameters: 100%

Test coverage

Line coverage

–

Expression

–

Tests / Examples

–

Functions

9 7 exported

Complexity

9.9 avg / 19 max

Call network

9 nodes / 6 edges

Test coverage has not been measured for this package yet; nodes fall back to a neutral fill.

Call graph

Open call graph →

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Lowest coverage

Per-function coverage is not measured for this package yet.

People & History

People (2)

Maintainer (1)

Alejandro Ochoa

Author, Maintainer

Authors (2)

Alejandro Ochoa

Author, Maintainer

Tiffany Tu

Author

Release timeline

1 release. R releases are shown for context.

1.0.0Latest
2026-05-12 · current release
R
R 4.6.0 released · 2026-04-24

Package metadata

First published: 2026-05-12
Total releases: 1 / 1 yrs
License: GPL (>= 3) OSI
Download size: not tracked yet
Installed size: not tracked yet
With dependencies: not tracked yet