bbssr

1.0.2

Blinded Sample Size Re-Estimation for Binary Endpoints

0packages depend

2.3Kdownloads / year

96.6%test coverage

13/13checks pass

Overview

About

Maintained by Gosuke HommaFirst published 2025-06-181 releasesCRAN page ↗GitHub ↗

Provides comprehensive tools for blinded sample size re-estimation (BSSR) in two-arm clinical trials with binary endpoints. Unlike traditional fixed-sample designs, BSSR allows adaptive sample size adjustments during trials while maintaining statistical integrity and study blinding. Implements five exact statistical tests: Pearson chi-squared, Fisher exact, Fisher mid-p, Z-pooled exact unconditional, and Boschloo exact unconditional tests. Supports restricted, unrestricted, and weighted BSSR approaches with exact Type I error control. Statistical methods based on Mehrotra et al. (2003) doi:10.1111/1541-0420.00051 and Kieser (2020) doi:10.1007/978-3-030-49528-2_21.

Install

R (CRAN)pak (dev)Ubuntu (r2u)

install.packages("bbssr", repos = "https://cloud.r-project.org/")

Installs the current CRAN release. Prebuilt binaries on Windows and macOS.

if (!requireNamespace("pak", quietly = TRUE))
  install.packages("pak", repos = "https://cloud.r-project.org/")
pak::pak("gosukehommaEX/bbssr")

Development version from gosukehommaEX/bbssr. Installs pak first if it is not already available.

Release

# enable cranapt (r2u) if it is not already set up, then install
grep -rqs r2u.stat.illinois.edu /etc/apt/sources.list /etc/apt/sources.list.d/ \
  || curl -fsSL https://raw.githubusercontent.com/eddelbuettel/r2u/master/inst/scripts/add_cranapt_noble.sh | sudo bash
sudo apt install -y r-cran-bbssr

Fast Ubuntu binaries via r2u (no compilation). The cranapt setup runs once and is skipped when it is already enabled.

bspm (used by r2u) also needs make: sudo apt install make

Health

CRAN checks

13OK

Slowest check: 5.7 min · r-oldrel-windows-x86_64

Check history

OK2026-03-10
14 OK · 0 NOTE · 0 WARNING · 0 ERROR · 0 FAILURE

Documentation

Documentation signals are not tracked yet for this package.

Downloads

2.3K

CRAN downloads in the past year

Rank #18,636 · ~6/day · ~192/mo

bbssr Releases R versions

Daily download trend is not available in this view yet.

22430 days

61690 days

2.3K1 year

Compare downloads with other packages →

Also on120 r2u

Repository

GitHub ↗ gosukehommaex/bbssr

2Stars

0Forks

0Open issues

0Open PRs

0Releases

47Commits

1Contributors

clinical-trialspower-calculationsample-size-calculationbinary-endpoints

47 commits · Last activity 2025-06-18 · 0% stars, 30d

Repository practices

Upstream repositoryBeta

4 development-tooling and community-health practices detected across 3 families in the upstream repository

Checks run against github.com/gosukehommaex/bbssr on 2026-07-19.

Continuous integration (1)

GitHub Actions

CRAN release process (2)

cran-comments.mdCRAN-SUBMISSION

Lint, format, editor (1)

RStudio project

How this is detected·Detection ruleset v1 (2026-07-18)

Dependencies

Declared dependencies

11 external dependencies (excludes base and recommended)

Depends (1)

R >= 3.5.0

Imports (2)

fpComparestats

LinkingTo (0)

none

Suggests (10)

testthat knitr rmarkdown dplyr ggplot2 tibble tidyr Exact exact2x2 microbenchmark

Enhances (0)

none

Dependency license breakdown →

Reverse dependencies

0direct

0indirect

Nothing depends on this yet.

Code & Tests

People & History

People (1)

Maintainer (1)

Gosuke Homma

Author, Maintainer

Authors (1)

Gosuke Homma

Author, Maintainer

Package Timeline

1 release. R releases are shown for context.

R
R 4.6.0 released · 2026-04-24
1.0.2Latest
2026-03-10 · current release
R
R 4.5.0 released · 2025-04-11

Package metadata

First published: 2025-06-18
Total releases: 1 / 1 yrs
License: MIT + file LICENSE OSI
Download size: 761 KB
Installed size: not tracked yet
With dependencies: not tracked yet

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