ZetaSuite
1.0.3Analyze High-Dimensional High-Throughput Dataset and Quality Control Single-Cell RNA-Seq
Overview
The advent of genomic technologies has enabled the generation of two-dimensional or even multi-dimensional high-throughput data, e.g., monitoring multiple changes in gene expression in genome-wide siRNA screens across many different cell types (E Robert McDonald 3rd (2017) <doi: 10.1016/j.cell.2017.07.005> and Tsherniak A (2017) <doi: 10.1016/j.cell.2017.06.010>) or single cell transcriptomics under different experimental conditions. We found that simple computational methods based on a single statistical criterion is no longer adequate for analyzing such multi-dimensional data. We herein introduce 'ZetaSuite', a statistical package initially designed to score hits from two-dimensional RNAi screens.We also illustrate a unique utility of 'ZetaSuite' in analyzing single cell transcriptomics to differentiate rare cells from damaged ones (Vento-Tormo R (2018) <doi: 10.1038/s41586-018-0698-6>). In 'ZetaSuite', we have the following steps: QC of input datasets, normalization using Z-transformation, Zeta score calculation and hits selection based on defined Screen Strength.
Install
Health
- NOTE r-devel-linux-x86_64-debian-gcc
- NOTE2026-08-0112 OK · 1 NOTE · 0 WARNING · 0 ERROR · 0 FAILURE
- OK2026-06-0913 OK · 0 NOTE · 0 WARNING · 0 ERROR · 0 FAILURE
- ERROR2026-06-0812 OK · 0 NOTE · 0 WARNING · 1 ERROR · 0 FAILURE
- OK2026-03-1014 OK · 0 NOTE · 0 WARNING · 0 ERROR · 0 FAILURE
Documentation
- Examples that run
- 93%
- Documented parameters
- 100%
- Return-value docs
- 100%
- References docs
- 7%
Downloads
Repository
Repository practices
Checks run against github.com/junhuili1017/zetasuite on 2026-07-30.
No development-tooling practices detected in the upstream repository.
Dependencies
Nothing depends on this yet.
Code & Tests
Datasets
People & History
4 releases. Pick two to compare their code metrics. R releases are shown for context.
Package metadata
- First published
- 2022-03-31
- Total releases
- 4 / 4 yrs
- License
- MIT + file LICENSE OSI
- Minimum R
- ≥ 2.10
- Bundled data
- 3.5 MB / 8 files
- Download size
- 4.2 MB
- Installed size
- not tracked yet
- With dependencies
- not tracked yet