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SimSeq

1.4.0

Nonparametric Simulation of RNA-Seq Data

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Overview

About
Maintained by Samuel BenidtFirst published 2014-02-184 releasesCRAN page ↗

RNA sequencing analysis methods are often derived by relying on hypothetical parametric models for read counts that are not likely to be precisely satisfied in practice. Methods are often tested by analyzing data that have been simulated according to the assumed model. This testing strategy can result in an overly optimistic view of the performance of an RNA-seq analysis method. We develop a data-based simulation algorithm for RNA-seq data. The vector of read counts simulated for a given experimental unit has a joint distribution that closely matches the distribution of a source RNA-seq dataset provided by the user. Users control the proportion of genes simulated to be differentially expressed (DE) and can provide a vector of weights to control the distribution of effect sizes. The algorithm requires a matrix of RNA-seq read counts with large sample sizes in at least two treatment groups. Many datasets are available that fit this standard.

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  • NOTE2026-03-10
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Dependencies

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1 external dependency (excludes base and recommended)
Depends (1)
R >= 2.10.0
Imports (1)
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Listed in earlier versions (1)
no longer listed · 1.0.0 to 1.4.0
Package Timeline

4 releases. Pick two to compare their code metrics. R releases are shown for context.

  • R
    R 4.6.0 released · 2026-04-24
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    R 4.5.0 released · 2025-04-11
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    R 4.4.0 released · 2024-04-24
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    R 4.3.0 released · 2023-04-21
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    R 4.2.0 released · 2022-04-22
  • R
    R 4.1.0 released · 2021-05-18
  • R
    R 4.0.0 released · 2020-04-24
  • R
    R 3.6.0 released · 2019-04-26
  • R
    R 3.5.0 released · 2018-04-23
  • R
    R 3.4.0 released · 2017-04-21
  • R
    R 3.3.0 released · 2016-05-03
  • 1.4.0Latest
    2015-11-23 · current release · diff ↗
  • R
    R 3.2.0 released · 2015-04-16
  • 1.3.0
    2015-03-07 · diff ↗
  • 1.2.0
    2014-12-10 · diff ↗
  • R
    R 3.1.0 released · 2014-04-10
Show 2 earlier events
  • 1.0.0
    2014-02-18
  • R
    R 3.0.0 released · 2013-04-03

Package metadata

First published
2014-02-18
Total releases
4 / 12 yrs
License
GPL (>= 2) OSI
Minimum R
≥ 2.10.0
Bundled data
4.2 MB / 2 files
Download size
4.2 MB
Installed size
not tracked yet
With dependencies
not tracked yet
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