PFIM

7.0.3

Population Fisher Information Matrix

0packages depend

5Kdownloads / year

22.0%test coverage

11/13checks pass

Overview

About

Maintained by Romain LerouxFirst published 2022-06-2410 releasesCRAN page ↗GitHub ↗

Evaluate or optimize designs for nonlinear mixed effects models using the Fisher Information matrix. Methods used in the package refer to Mentré F, Mallet A, Baccar D (1997) doi:10.1093/biomet/84.2.429, Retout S, Comets E, Samson A, Mentré F (2007) doi:10.1002/sim.2910, Bazzoli C, Retout S, Mentré F (2009) doi:10.1002/sim.3573, Le Nagard H, Chao L, Tenaillon O (2011) doi:10.1186/1471-2148-11-326, Combes FP, Retout S, Frey N, Mentré F (2013) doi:10.1007/s11095-013-1079-3 and Seurat J, Tang Y, Mentré F, Nguyen TT (2021) doi:10.1016/j.cmpb.2021.106126.

Install

R (CRAN)pak (dev)Ubuntu (r2u)openSUSE (OBS)

install.packages("PFIM", repos = "https://cloud.r-project.org/")

Installs the current CRAN release. Prebuilt binaries on Windows and macOS.

if (!requireNamespace("pak", quietly = TRUE))
  install.packages("pak", repos = "https://cloud.r-project.org/")
pak::pak("packagePFIM/PFIM")

Development version from packagePFIM/PFIM. Installs pak first if it is not already available.

Release

# enable cranapt (r2u) if it is not already set up, then install
grep -rqs r2u.stat.illinois.edu /etc/apt/sources.list /etc/apt/sources.list.d/ \
  || curl -fsSL https://raw.githubusercontent.com/eddelbuettel/r2u/master/inst/scripts/add_cranapt_noble.sh | sudo bash
sudo apt install -y r-cran-pfim

Fast Ubuntu binaries via r2u (no compilation). The cranapt setup runs once and is skipped when it is already enabled.

bspm (used by r2u) also needs make: sudo apt install make

# add the autoCRAN OBS repo (Tumbleweed) if it is missing, then install
zypper -q lr | grep -qi autoCRAN \
  || sudo zypper addrepo https://download.opensuse.org/repositories/devel:/languages:/R:/autoCRAN/openSUSE_Tumbleweed/devel:languages:R:autoCRAN.repo
sudo zypper install -y R-PFIM

RPMs auto-built from CRAN on openSUSE OBS (Tumbleweed).

Health

CRAN checks

2NOTE11OK

Failing flavors

NOTE r-devel-linux-x86_64-debian-clang
NOTE r-devel-linux-x86_64-debian-gcc

Slowest check: 4.7 min · r-devel-linux-x86_64-fedora-clang

Check history

NOTE2026-07-11
12 OK · 1 NOTE · 0 WARNING · 0 ERROR · 0 FAILURE
OK2026-03-10
14 OK · 0 NOTE · 0 WARNING · 0 ERROR · 0 FAILURE

Documentation

Documentation signals are not tracked yet for this package.

Downloads

CRAN downloads in the past year

Rank #6,069 · ~14/day · ~415/mo

PFIM Releases R versions

Daily download trend is not available in this view yet.

34130 days

1.6K90 days

5K1 year

Compare downloads with other packages →

Also on170 r2u30 autocran

Repository

GitHub ↗ packagepfim/pfim

2Stars

2Forks

0Open issues

0Open PRs

0Releases

73Commits

2Contributors

73 commits · Last activity 2026-05-29 · 0% stars, 30d

Repository practices

Upstream repositoryBeta

3 development-tooling and community-health practices detected across 2 families in the upstream repository

Checks run against github.com/packagepfim/pfim on 2026-07-19.

Lint, format, editor (2)

EditorConfigRStudio project

Git structural (1)

.gitattributes

How this is detected·Detection ruleset v1 (2026-07-18)

Dependencies

Declared dependencies

16 external dependencies (excludes base and recommended)

Depends (1)

R >= 4.0.0

Imports (17)

utilsinline DerivmethodsdeSolve purrr stringr S7Matrixggplot2 Rcpp RcppArmadillo pracma kableExtra tibble scales knitr

LinkingTo (0)

none

Suggests (2)

rmarkdown testthat

Enhances (0)

none

Dependency license breakdown →

Reverse dependencies

0direct

0indirect

Nothing depends on this yet.

Code & Tests

People & History

People (3)

Maintainer (1)

Romain Leroux

Author, Maintainer

Authors (2)

Romain Leroux

Author, Maintainer

France Mentré

Author

Contributors (1)

Jérémy Seurat

Contributor

Listed in earlier versions (13)

Caroline Bazzoli

no longer listed · 5.0

Emmanuelle Comets

no longer listed · 5.0 to 6.0.3

Anne Dubois

no longer listed · 5.0

Cyrielle Dumont

no longer listed · 5.0

Hervé Le Nagard

no longer listed · 5.0

Giulia Lestini

no longer listed · 5.0

Thi Huyen Tram Nguyen

no longer listed · 5.0

Thu Thuy Nguyen

no longer listed · 5.0

Package Timeline

10 releases. R releases are shown for context.

R
R 4.6.0 released · 2026-04-24
7.0.3Latest
2026-04-09 · current release · diff ↗
7.0.2
2026-01-30 · diff ↗
7.0.1
2025-11-26 · diff ↗
7.0
2025-07-02 · diff ↗
R
R 4.5.0 released · 2025-04-11
6.1
2024-10-23 · diff ↗
R
R 4.4.0 released · 2024-04-24
6.0.3
2024-03-23 · diff ↗
6.0.2
2023-11-24 · diff ↗
6.0.1
2023-11-20 · diff ↗
6.0
2023-11-08 · diff ↗
R
R 4.3.0 released · 2023-04-21
5.0
2022-06-24
R
R 4.2.0 released · 2022-04-22

Package metadata

First published: 2022-06-24
Total releases: 10 / 4 yrs
License: GPL (>= 3) OSI
Download size: 167 KB
Installed size: not tracked yet
With dependencies: not tracked yet

Appears in task views

Analysis of Pharmacokinetic Data

Report a problem with this page →