OSNMTF
0.1.0Orthogonal Sparse Non-Negative Matrix Tri-Factorization
Overview
A novel method to implement cancer subtyping and subtype specific drug targets identification via non-negative matrix tri-factorization. To improve the interpretability, we introduce orthogonal constraint to the row coefficient matrix and column coefficient matrix. To meet the prior knowledge that each subtype should be strongly associated with few gene sets, we introduce sparsity constraint to the association sub-matrix. The average residue was introduced to evaluate the row and column cluster numbers. This is part of the work "Liver Cancer Analysis via Orthogonal Sparse Non-Negative Matrix Tri- Factorization" which will be submitted to BBRC.
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- NOTE r-devel-linux-x86_64-debian-clang
- NOTE r-devel-linux-x86_64-debian-gcc
- NOTE2026-03-109 OK · 5 NOTE · 0 WARNING · 0 ERROR · 0 FAILURE
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1 release. R releases are shown for context.
- RR 4.6.0 released · 2026-04-24
- 0.1.0Latest2026-03-10 · current release
- RR 4.5.0 released · 2025-04-11
Package metadata
- First published
- 2019-11-28
- Total releases
- 1 / 7 yrs
- License
- GPL (>= 2) OSI
- Minimum R
- ≥ 3.4.4
- Download size
- 322 KB
- Installed size
- not tracked yet
- With dependencies
- not tracked yet