MedianaDesigner

0.13

Power and Sample Size Calculations for Clinical Trials

0packages depend

3.4Kdownloads / year

99.7%test coverage

0/13checks pass

Overview

About

Maintained by Alex DmitrienkoFirst published 2021-07-0814 releasesCRAN page ↗GitHub ↗

Efficient simulation-based power and sample size calculations are supported for a broad class of late-stage clinical trials. The following modules are included in the package: Adaptive designs with data-driven sample size or event count re-estimation, Adaptive designs with data-driven treatment selection, Adaptive designs with data-driven population selection, Optimal selection of a futility stopping rule, Event prediction in event-driven trials, Adaptive trials with response-adaptive randomization (experimental module), Traditional trials with multiple objectives (experimental module). Traditional trials with cluster-randomized designs (experimental module).

Install

R (CRAN)pak (dev)Ubuntu (r2u)

install.packages("MedianaDesigner", repos = "https://cloud.r-project.org/")

Installs the current CRAN release. Prebuilt binaries on Windows and macOS.

if (!requireNamespace("pak", quietly = TRUE))
  install.packages("pak", repos = "https://cloud.r-project.org/")
pak::pak("medianasoft/MedianaDesigner")

Development version from medianasoft/MedianaDesigner. Installs pak first if it is not already available.

Release

# enable cranapt (r2u) if it is not already set up, then install
grep -rqs r2u.stat.illinois.edu /etc/apt/sources.list /etc/apt/sources.list.d/ \
  || curl -fsSL https://raw.githubusercontent.com/eddelbuettel/r2u/master/inst/scripts/add_cranapt_noble.sh | sudo bash
sudo apt install -y r-cran-medianadesigner

Fast Ubuntu binaries via r2u (no compilation). The cranapt setup runs once and is skipped when it is already enabled.

bspm (used by r2u) also needs make: sudo apt install make

Health

CRAN checks

13NOTE

Failing flavors

NOTE r-devel-linux-x86_64-debian-clang
NOTE r-devel-linux-x86_64-debian-gcc
NOTE r-devel-linux-x86_64-fedora-clang
NOTE r-devel-linux-x86_64-fedora-gcc
NOTE r-devel-windows-x86_64
NOTE r-oldrel-macos-arm64
NOTE r-oldrel-macos-x86_64
NOTE r-oldrel-windows-x86_64
NOTE r-patched-linux-x86_64
NOTE r-release-linux-x86_64
NOTE r-release-macos-arm64
NOTE r-release-macos-x86_64
NOTE r-release-windows-x86_64

Slowest check: 13.0 min · r-devel-linux-x86_64-fedora-clang

Code health

Yes

Tests · ratio 0.67

99.7%

Coverage · measured lines

100%

Documentation · exports

Dependencies · direct

Check history

NOTE2026-06-09
0 OK · 13 NOTE · 0 WARNING · 0 ERROR · 0 FAILURE
ERROR2026-06-08
0 OK · 12 NOTE · 0 WARNING · 1 ERROR · 0 FAILURE
NOTE2026-04-22
0 OK · 14 NOTE · 0 WARNING · 0 ERROR · 0 FAILURE
ERROR2026-04-18
0 OK · 13 NOTE · 0 WARNING · 1 ERROR · 0 FAILURE
NOTE2026-03-10
0 OK · 14 NOTE · 0 WARNING · 0 ERROR · 0 FAILURE

Documentation

READMENoVignettesNopkgdown siteNoNEWSNoCode of conductNoContributing guideNo

Examples that run: 100%
Documented parameters: 100%
Return-value docs: 100%
References docs: 3%

Downloads

3.4K

CRAN downloads in the past year

Rank #11,662 · ~9/day · ~286/mo

Releases R versions

Daily download trend is not available in this view yet.

30330 days

89390 days

3.4K1 year

Compare downloads with other packages →

Also on435 r2u

Repository

GitHub ↗ medianasoft/medianadesigner

23Stars

3Forks

1Open issues

0Open PRs

0Releases

15Commits

3Contributors

15 commits · Last activity 2023-08-28 · +4.5% stars, 30d

Stars over time

2025-04-23 · 202026-07-07 · 23

Repository practices

Upstream repositoryBeta

2 development-tooling and community-health practices detected across 2 families in the upstream repository

Checks run against github.com/medianasoft/medianadesigner on 2026-07-19.

Continuous integration (1)

GitHub Actions

Coverage (1)

Codecov

How this is detected·Detection ruleset v1 (2026-07-18)

Dependencies

Declared dependencies

20 external dependencies (excludes base and recommended)

Depends (1)

R >= 3.1.2

Imports (18)

Rcpp RcppNumericalmethodsofficer flextable devEMF mvtnorm shiny shinydashboard shinyMatrix foreachparalleldoParallelMASSrootSolve lme4 lmerTest pbkrtest

LinkingTo (3)

Rcpp RcppEigen RcppNumerical

Suggests (2)

testthat doRNG

Enhances (0)

none

Dependency license breakdown →

Reverse dependencies

0direct

0indirect

Nothing depends on this yet.

Code & Tests

Datasets

People & History

People (1)

Maintainer (1)

Alex Dmitrienko

Author, Maintainer

Authors (1)

Alex Dmitrienko

Author, Maintainer

Package Timeline

14 releases. Pick two to compare their code metrics. R releases are shown for context.

R
R 4.6.0 released · 2026-04-24
R
R 4.5.0 released · 2025-04-11
R
R 4.4.0 released · 2024-04-24
0.13Latest
2023-08-28 · current release · diff ↗
R
R 4.3.0 released · 2023-04-21
0.12
2023-01-12 · diff ↗
0.11
2022-12-16 · diff ↗
0.10
2022-11-01 · diff ↗
0.9
2022-10-28 · diff ↗
unarchivedReturned to CRAN
2022-10-28
archivedRemoved from CRAN
2022-07-09
check problems were not corrected in time
0.8
2022-06-24 · diff ↗
R
R 4.2.0 released · 2022-04-22
0.7
2021-12-19 · diff ↗
0.6
2021-11-01 · diff ↗
unarchivedReturned to CRAN
2021-11-01

Show 10 earlier events

archivedRemoved from CRAN
2021-10-22
check problems were not corrected in time
0.5
2021-10-11 · diff ↗
0.4
2021-10-06 · diff ↗
0.3
2021-09-20 · diff ↗
0.2.3
2021-08-16 · diff ↗
0.2.2
2021-07-28 · diff ↗
unarchivedReturned to CRAN
2021-07-28
archivedRemoved from CRAN
2021-07-23
check issues were not corrected in time
0.2
2021-07-08
R
R 4.1.0 released · 2021-05-18

Package metadata

First published: 2021-07-08
Total releases: 14 / 5 yrs
License: GPL-3 OSI
Minimum R: ≥ 3.1.2
Bundled data: 4.8 KB / 1 file
Download size: 188 KB
Installed size: not tracked yet
With dependencies: not tracked yet

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