Mediana

1.0.8

Clinical Trial Simulations

0packages depend

3.7Kdownloads / year

–test coverage

11/13checks pass

Overview

About

Maintained by Gautier PauxFirst published 2015-07-269 releasesCRAN page ↗GitHub ↗

Provides a general framework for clinical trial simulations based on the Clinical Scenario Evaluation (CSE) approach. The package supports a broad class of data models (including clinical trials with continuous, binary, survival-type and count-type endpoints as well as multivariate outcomes that are based on combinations of different endpoints), analysis strategies and commonly used evaluation criteria.

Install

R (CRAN)pak (dev)Ubuntu (r2u)Fedora (COPR)openSUSE (OBS)

install.packages("Mediana", repos = "https://cloud.r-project.org/")

Installs the current CRAN release. Prebuilt binaries on Windows and macOS.

if (!requireNamespace("pak", quietly = TRUE))
  install.packages("pak", repos = "https://cloud.r-project.org/")
pak::pak("gpaux/Mediana")

Development version from gpaux/Mediana. Installs pak first if it is not already available.

Release

# enable cranapt (r2u) if it is not already set up, then install
grep -rqs r2u.stat.illinois.edu /etc/apt/sources.list /etc/apt/sources.list.d/ \
  || curl -fsSL https://raw.githubusercontent.com/eddelbuettel/r2u/master/inst/scripts/add_cranapt_noble.sh | sudo bash
sudo apt install -y r-cran-mediana

Fast Ubuntu binaries via r2u (no compilation). The cranapt setup runs once and is skipped when it is already enabled.

bspm (used by r2u) also needs make: sudo apt install make

# enable the iucar/cran COPR if it is not already present, then install
ls /etc/yum.repos.d/*iucar*cran*.repo >/dev/null 2>&1 \
  || sudo dnf copr enable -y iucar/cran
sudo dnf install -y R-CRAN-Mediana

RPMs from the iucar/cran COPR, rebuilt from CRAN.

For install.packages() integration in R, also: sudo dnf install R-CoprManager

# add the autoCRAN OBS repo (Tumbleweed) if it is missing, then install
zypper -q lr | grep -qi autoCRAN \
  || sudo zypper addrepo https://download.opensuse.org/repositories/devel:/languages:/R:/autoCRAN/openSUSE_Tumbleweed/devel:languages:R:autoCRAN.repo
sudo zypper install -y R-Mediana

RPMs auto-built from CRAN on openSUSE OBS (Tumbleweed).

Health

CRAN checks

2NOTE11OK

Failing flavors

NOTE r-devel-linux-x86_64-debian-clang
NOTE r-devel-linux-x86_64-debian-gcc

Slowest check: 2.1 min · r-devel-linux-x86_64-fedora-clang

Code health

None

Tests · ratio 0.00

not tracked

Coverage

100%

Documentation · exports

Dependencies · direct

Check history

NOTE2026-03-10
12 OK · 2 NOTE · 0 WARNING · 0 ERROR · 0 FAILURE

Documentation

READMEYes · 501 wordsVignettesYes · dynamicpkgdown siteNoNEWSYes · 100% structuredCode of conductNoContributing guideNo

Examples that run: 84%
Documented parameters: 100%
Return-value docs: 26%
References docs: 100%

Downloads

3.7K

CRAN downloads in the past year

Rank #10,523 · ~10/day · ~311/mo

Releases R versions

Daily download trend is not available in this view yet.

30830 days

97690 days

3.7K1 year

Compare downloads with other packages →

Also on89 r2u3 autocran71 c2d4u

Repository

GitHub ↗ gpaux/mediana

32Stars

3Forks

2Open issues

0Open PRs

8Releases

95Commits

4Contributors

rclinical-trialsclinical-trial-simulationssimulationsbiostatistics

95 commits · Last activity 2023-08-29 · 0% stars, 30d

Stars over time

2025-03-20 · 292026-07-07 · 32

Repository practices

Upstream repositoryBeta

2 development-tooling and community-health practices detected across 2 families in the upstream repository

Checks run against github.com/gpaux/mediana on 2026-07-31.

Docs source (1)

README.Rmd

Lint, format, editor (1)

RStudio project

How this is detected·Detection ruleset v1 (2026-07-18)

Dependencies

Declared dependencies

9 external dependencies (excludes base and recommended)

Depends (0)

none

Imports (8)

doParallel doRNG foreachMASSmvtnormstatssurvivalutils

LinkingTo (0)

none

Suggests (5)

flextable knitr officer rmarkdown pander

Enhances (0)

none

Dependency license breakdown →

Reverse dependencies

0direct

0indirect

Nothing depends on this yet.

Code & Tests

People & History

People (0)

Author records are not tracked yet for this package.

Listed in earlier versions (2)

Alex Dmitrienko.

no longer listed · 1.0 to 1.0.8

Gautier Paux

no longer listed · 1.0 to 1.0.8

Package Timeline

9 releases. Pick two to compare their code metrics. R releases are shown for context.

R
R 4.6.0 released · 2026-04-24
R
R 4.5.0 released · 2025-04-11
R
R 4.4.0 released · 2024-04-24
R
R 4.3.0 released · 2023-04-21
R
R 4.2.0 released · 2022-04-22
R
R 4.1.0 released · 2021-05-18
R
R 4.0.0 released · 2020-04-24
1.0.8Latest
2019-05-08 · current release · diff ↗
R
R 3.6.0 released · 2019-04-26
1.0.7
2018-07-16 · diff ↗
R
R 3.5.0 released · 2018-04-23
1.0.6
2018-02-13 · diff ↗
1.0.5
2017-05-25 · diff ↗
R
R 3.4.0 released · 2017-04-21
1.0.4
2017-02-07 · diff ↗
1.0.3
2016-08-25 · diff ↗

Show 5 earlier events

R
R 3.3.0 released · 2016-05-03
1.0.2
2015-11-16 · diff ↗
1.0.1
2015-07-26 · diff ↗
1.0
2015-07-26
R
R 3.2.0 released · 2015-04-16

Package metadata

First published: 2015-07-26
Total releases: 9 / 11 yrs
License: GPL-2 OSI
Download size: 328 KB
Installed size: not tracked yet
With dependencies: not tracked yet

Appears in task views

Clinical Trial Design, Monitoring, Analysis and Reporting

Report a problem with this page →