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CompAREdesign

Statistical Functions for the Design of Studies with Composite Endpoints

v2.4.0 · Mar 4, 2025 · GPL-3

Description

It has been designed to calculate the required sample size in randomized clinical trials with composite endpoints. It also calculates the expected effect and the probability of observing the composite endpoint, among others. The methodology can be found in Bofill & Gómez (2019) <doi:10.1002/sim.8092> and Gómez & Lagakos (2013) <doi:10.1002/sim.5547>.

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OK 14 OK · 0 NOTE · 0 WARNING · 0 ERROR · 0 FAILURE Mar 9, 2026

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Dependencies Reverse dependencies copula ggplot2 ggpubr rootSolve numDeriv eselect CompAREdesign

Version History

new 2.4.0 Mar 9, 2026