BPrinStratTTE

0.0.7

Causal Effects in Principal Strata Defined by Antidrug Antibodies

0packages depend

2.8Kdownloads / year

2.3%test coverage

0/13checks pass

Overview

About

Maintained by Christian StockFirst published 2023-12-202 releasesCRAN page ↗GitHub ↗

Bayesian models to estimate causal effects of biological treatments on time-to-event endpoints in clinical trials with principal strata defined by the occurrence of antidrug antibodies. The methodology is based on Frangakis and Rubin (2002) doi:10.1111/j.0006-341x.2002.00021.x and Imbens and Rubin (1997) doi:10.1214/aos/1034276631, and here adapted to a specific time-to-event setting.

Install

R (CRAN)pak (dev)Ubuntu (r2u)openSUSE (OBS)

install.packages("BPrinStratTTE", repos = "https://cloud.r-project.org/")

Installs the current CRAN release. Prebuilt binaries on Windows and macOS.

if (!requireNamespace("pak", quietly = TRUE))
  install.packages("pak", repos = "https://cloud.r-project.org/")
pak::pak("Boehringer-Ingelheim/BPrinStratTTE")

Development version from Boehringer-Ingelheim/BPrinStratTTE. Installs pak first if it is not already available.

Release

# enable cranapt (r2u) if it is not already set up, then install
grep -rqs r2u.stat.illinois.edu /etc/apt/sources.list /etc/apt/sources.list.d/ \
  || curl -fsSL https://raw.githubusercontent.com/eddelbuettel/r2u/master/inst/scripts/add_cranapt_noble.sh | sudo bash
sudo apt install -y r-cran-bprinstrattte

Fast Ubuntu binaries via r2u (no compilation). The cranapt setup runs once and is skipped when it is already enabled.

bspm (used by r2u) also needs make: sudo apt install make

# add the autoCRAN OBS repo (Tumbleweed) if it is missing, then install
zypper -q lr | grep -qi autoCRAN \
  || sudo zypper addrepo https://download.opensuse.org/repositories/devel:/languages:/R:/autoCRAN/openSUSE_Tumbleweed/devel:languages:R:autoCRAN.repo
sudo zypper install -y R-BPrinStratTTE

RPMs auto-built from CRAN on openSUSE OBS (Tumbleweed).

Health

CRAN checks

13NOTE

Failing flavors

NOTE r-devel-linux-x86_64-debian-clang
NOTE r-devel-linux-x86_64-debian-gcc
NOTE r-devel-linux-x86_64-fedora-clang
NOTE r-devel-linux-x86_64-fedora-gcc
NOTE r-devel-windows-x86_64
NOTE r-oldrel-macos-arm64
NOTE r-oldrel-macos-x86_64
NOTE r-oldrel-windows-x86_64
NOTE r-patched-linux-x86_64
NOTE r-release-linux-x86_64
NOTE r-release-macos-arm64
NOTE r-release-macos-x86_64
NOTE r-release-windows-x86_64

Slowest check: 9.0 min · r-oldrel-windows-x86_64

Code health

Yes

Tests · ratio 0.00

2.3%

Coverage · measured lines

100%

Documentation · exports

Dependencies · direct

Check history

NOTE2026-06-09
0 OK · 13 NOTE · 0 WARNING · 0 ERROR · 0 FAILURE
ERROR2026-06-08
0 OK · 12 NOTE · 0 WARNING · 1 ERROR · 0 FAILURE
NOTE2026-04-22
1 OK · 13 NOTE · 0 WARNING · 0 ERROR · 0 FAILURE
ERROR2026-04-18
1 OK · 12 NOTE · 0 WARNING · 1 ERROR · 0 FAILURE
NOTE2026-03-10
1 OK · 13 NOTE · 0 WARNING · 0 ERROR · 0 FAILURE

Documentation

READMEYes · 557 wordsVignettesNopkgdown siteNoNEWSYes · 100% structuredCode of conductNoContributing guideNo

Examples that run: 100%
Documented parameters: 100%
Return-value docs: 100%
References docs: 6%

Downloads

2.8K

CRAN downloads in the past year

Rank #11,309 · ~8/day · ~237/mo

Releases R versions

Daily download trend is not available in this view yet.

43230 days

92390 days

2.8K1 year

Compare downloads with other packages →

Also on470 r2u43 autocran

Repository

GitHub ↗ boehringer-ingelheim/bprinstrattte

0Stars

0Forks

0Open issues

0Open PRs

2Releases

131Commits

3Contributors

principal-stratificationr-packagebayesian-methodscausal-inferenceestimandclinical-trialsimulationmcmc-methods

License GPL-3.0 · 131 commits · Last activity 2024-04-16

Releases over time

2024-04-16 · 22026-07-07 · 2

Repository practices

Upstream repositoryBeta

6 development-tooling and community-health practices detected across 5 families in the upstream repository

Checks run against github.com/boehringer-ingelheim/bprinstrattte on 2026-07-19.

Continuous integration (1)

GitHub Actions

CRAN release process (2)

cran-comments.mdCRAN-SUBMISSION

Docs source (1)

README.Rmd

Lint, format, editor (1)

RStudio project

Show all practices

Git structural (1)

.gitattributes

How this is detected·Detection ruleset v1 (2026-07-18)

Dependencies

Declared dependencies

17 external dependencies (excludes base and recommended)

Depends (1)

R >= 3.4.0

Imports (12)

dplyr furrr magrittrmethodspurrr Rcpp RcppParallel rstan rstantools (>= 2.4.0)statsstringr tibble

LinkingTo (6)

BH Rcpp RcppEigen RcppParallel rstan StanHeaders (>= 2.18.0)

Suggests (1)

spelling

Enhances (0)

none

Dependency license breakdown →

Reverse dependencies

0direct

0indirect

Nothing depends on this yet.

Code & Tests

People & History

People (3)

Maintainer (1)

Christian Stock

Author, Maintainer

Authors (2)

Christian Stock

Author, Maintainer

Emma Torrini

Author

Boehringer Ingelheim Pharma GmbH & Co. KG

Funders (1)

Boehringer Ingelheim Pharma GmbH & Co. KG

Package Timeline

2 releases. Pick two to compare their code metrics. R releases are shown for context.

R
R 4.6.0 released · 2026-04-24
R
R 4.5.0 released · 2025-04-11
R
R 4.4.0 released · 2024-04-24
0.0.7Latest
2024-04-13 · current release · diff ↗
0.0.2
2023-12-20
R
R 4.3.0 released · 2023-04-21

Package metadata

First published: 2023-12-20
Total releases: 2 / 3 yrs
License: GPL (>= 3) OSI
Minimum R: ≥ 3.4.0
Download size: 37 KB
Installed size: not tracked yet
With dependencies: not tracked yet

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