synergyfinder
Bioc currentCalculate and Visualize Synergy Scores for Drug Combinations
Release Lineage
Entered 3.4 · Oct 18, 2016
Current · Requires R 4.6
Description
Efficient implementations for analyzing pre-clinical multiple drug combination datasets. It provides efficient implementations for 1.the popular synergy scoring models, including HSA, Loewe, Bliss, and ZIP to quantify the degree of drug combination synergy; 2. higher order drug combination data analysis and synergy landscape visualization for unlimited number of drugs in a combination; 3. statistical analysis of drug combination synergy and sensitivity with confidence intervals and p-values; 4. synergy barometer for harmonizing multiple synergy scoring methods to provide a consensus metric of synergy; 5. evaluation of synergy and sensitivity simultaneously to provide an unbiased interpretation of the clinical potential of the drug combinations. Based on this package, we also provide a web application (http://www.synergyfinder.org) for users who prefer graphical user interface.
Test coverage
Line coverage
–
Expression
–
Tests / Examples
–
Functions
47 32 exported
Complexity
7.4 avg / 33 max
Call network
47 nodes / 65 edges
Test coverage is not measured for Bioconductor packages; nodes fall back to a neutral fill.
Call graph
Open call graph →Lowest coverage
Per-function coverage is not measured for this package yet.
Code
Structure
Lines of code
11,084
Files
91
Compiled share
0%
Has compiled src
No
Language breakdown
API
Exported functions
32
Internal functions
15
Recent export changes
Testing & CI
Has tests
No
Test-to-code ratio
0.00
testthat edition
–
CI present
Yes
CI type
["travis"]
PR gated
No
Docs
Roxygen coverage
100%
Health & Security signals
Informational signals; not verdicts.
on.exit coverage
0%
Unsafe pattern score
0
Dep constraint coverage
100%
Secret pattern count
0
Bundled 3rd-party code
2 items
Portability & License
Min R version
4.0.0
System requirements
–
C++ standard
–
License
Mozilla Public License 2.0
License flags
not SPDX, not OSI
History
Versions
20
First release
2016-10-17
Latest release
2026-04-28
Avg cadence
175 days
Cold removal rate
100%
Dep drift
25
LOC over versions
Per-file churn detail lives in the source pipeline: https://github.com/r-observatory/bioc-code-metrics.
Documentation
- Examples that run
- 95%
- Documented parameters
- 99%
- Return-value docs
- 100%
- References docs
- 16%
Topics
People
- Shuyu Zheng author maintainer
- Jing Tang author
Cite
Cite this package
Run in R for the authors' preferred citation:
citation("synergyfinder")This is what citation() produces when a package has no citation file of its own. If it prints something else, use that.
Cite the R Observatory
For a number measured here: a download total, a coverage figure, an archival date.
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