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gscreend

Bioc current

Analysis of pooled genetic screens

v1.26.0 · software · GPL-3

Release Lineage

Entered 3.10 · Oct 30, 2019

Current · Requires R 4.6

1.0 In 14 of 49 releases 3.23

Description

Package for the analysis of pooled genetic screens (e.g. CRISPR-KO). The analysis of such screens is based on the comparison of gRNA abundances before and after a cell proliferation phase. The gscreend packages takes gRNA counts as input and allows detection of genes whose knockout decreases or increases cell proliferation.

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