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bacon

Bioc current

Controlling bias and inflation in association studies using the empirical null distribution

v1.40.0 · software · GPL (>= 2)

Release Lineage

Entered 3.3 · May 4, 2016

Current · Requires R 4.6

1.0 In 21 of 49 releases 3.23

Description

Bacon can be used to remove inflation and bias often observed in epigenome- and transcriptome-wide association studies. To this end bacon constructs an empirical null distribution using a Gibbs Sampling algorithm by fitting a three-component normal mixture on z-scores.

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