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Optimal Sample Size and Progression Criteria for Three-Outcome Trials
v1.0.3
·
Nov 7, 2025
·
MIT + file LICENSE
Description
Find the optimal decision rules (AKA progression criteria) and sample size for clinical trials with three (stop/pause/go) outcomes. Both binary and continuous endpoints can be accommodated, as can cases where an adjustment is planned following a pause outcome. For more details see Wilson et al. (2024) <doi:10.1186/s12874-024-02351-x>.
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OK 14 OK · 0 NOTE · 0 WARNING · 0 ERROR · 0 FAILURE Mar 9, 2026
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1.0.3
Mar 9, 2026