splinetrials
Facilitate Clinical Trials Analysis Using Natural Cubic Splines
v0.1.1
·
Jan 19, 2026
·
Apache License (>= 2)
Description
Create mixed models with repeated measures using natural cubic splines applied to an observed continuous time variable, as described by Donohue et al. (2023) <doi:10.1002/pst.2285>. Iterate through multiple covariance structure types until one converges. Categorize observed time according to scheduled visits. Perform subgroup analyses.
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| r-release-windows-x86_64 | OK |
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OK 14 OK · 0 NOTE · 0 WARNING · 0 ERROR · 0 FAILURE Mar 9, 2026
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0.1.1
Mar 9, 2026