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speff2trial

Semiparametric Efficient Estimation for a Two-Sample Treatment Effect

v1.0.5 · May 31, 2022 · GPL-2

Description

Performs estimation and testing of the treatment effect in a 2-group randomized clinical trial with a quantitative, dichotomous, or right-censored time-to-event endpoint. The method improves efficiency by leveraging baseline predictors of the endpoint. The inverse probability weighting technique of Robins, Rotnitzky, and Zhao (JASA, 1994) is used to provide unbiased estimation when the endpoint is missing at random.

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r-devel-linux-x86_64-debian-clang NOTE
r-devel-linux-x86_64-debian-gcc NOTE
r-devel-linux-x86_64-fedora-clang OK
r-devel-linux-x86_64-fedora-gcc OK
r-devel-macos-arm64 OK
r-devel-windows-x86_64 OK
r-oldrel-macos-arm64 OK
r-oldrel-macos-x86_64 OK
r-oldrel-windows-x86_64 OK
r-patched-linux-x86_64 OK
r-release-linux-x86_64 OK
r-release-macos-arm64 OK
r-release-macos-x86_64 OK
r-release-windows-x86_64 OK
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NOTE r-devel-linux-x86_64-debian-clang

CRAN incoming feasibility

Maintainer: ‘Michal Juraska <mjuraska@fredhutch.org>’

No Authors@R field in DESCRIPTION.
Please add one, modifying
  Authors@R: c(person(given = "Michal",
                      family = "Juraska",
                      role = c("aut", "cre"),
                      email = "mjuraska@fredhutch.org"),
               person(given = c("with", "contributions", "from", "Peter", "B."),
                      family = "Gilbert",
                      role = "aut",
                      email = "pgilbert@scharp.org"),
               person(given = "Xiaomin",
                      family = "Lu",
                      role = "aut",
                      email = "xlu2@phhp.ufl.edu"),
               person(given = "Min",
                      family = "Zhang",
                      role = "aut",
                      email = "mzhangst@umich.edu"),
               person(given = "Marie",
                      family = "Davidian",
                      role = "aut",
                      email = "davidian@stat.ncsu.edu"),
               person(given = c("Anastasios", "A."),
                      family = "Tsiatis",
                      role = "aut",
                      email = "tsiatis@stat.ncsu.edu"))
as necessary.
NOTE r-devel-linux-x86_64-debian-gcc

CRAN incoming feasibility

Maintainer: ‘Michal Juraska <mjuraska@fredhutch.org>’

No Authors@R field in DESCRIPTION.
Please add one, modifying
  Authors@R: c(person(given = "Michal",
                      family = "Juraska",
                      role = c("aut", "cre"),
                      email = "mjuraska@fredhutch.org"),
               person(given = c("with", "contributions", "from", "Peter", "B."),
                      family = "Gilbert",
                      role = "aut",
                      email = "pgilbert@scharp.org"),
               person(given = "Xiaomin",
                      family = "Lu",
                      role = "aut",
                      email = "xlu2@phhp.ufl.edu"),
               person(given = "Min",
                      family = "Zhang",
                      role = "aut",
                      email = "mzhangst@umich.edu"),
               person(given = "Marie",
                      family = "Davidian",
                      role = "aut",
                      email = "davidian@stat.ncsu.edu"),
               person(given = c("Anastasios", "A."),
                      family = "Tsiatis",
                      role = "aut",
                      email = "tsiatis@stat.ncsu.edu"))
as necessary.
OK r-devel-linux-x86_64-fedora-clang

*


            
OK r-devel-linux-x86_64-fedora-gcc

*


            
OK r-devel-macos-arm64

*


            
OK r-devel-windows-x86_64

*


            
OK r-oldrel-macos-arm64

*


            
OK r-oldrel-macos-x86_64

*


            
OK r-oldrel-windows-x86_64

*


            
OK r-patched-linux-x86_64

*


            
OK r-release-linux-x86_64

*


            
OK r-release-macos-arm64

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OK r-release-macos-x86_64

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OK r-release-windows-x86_64

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Check History

NOTE 12 OK · 2 NOTE · 0 WARNING · 0 ERROR · 0 FAILURE Mar 9, 2026
NOTE r-devel-linux-x86_64-debian-clang

CRAN incoming feasibility

Maintainer: ‘Michal Juraska <mjuraska@fredhutch.org>’

No Authors@R field in DESCRIPTION.
Please add one, modifying
  Authors@R: c(person(given = "Michal",
                      family = "Juraska",
                      role = c("aut", "cre"),
                      email = "mjuraska@fredhutch.org"),
               person(given = c("with", "contributions", "from", "Peter", "B."),
                      family = "Gilbert",
                      role = "aut",
                      email = "pgilbert@
NOTE r-devel-linux-x86_64-debian-gcc

CRAN incoming feasibility

Maintainer: ‘Michal Juraska <mjuraska@fredhutch.org>’

No Authors@R field in DESCRIPTION.
Please add one, modifying
  Authors@R: c(person(given = "Michal",
                      family = "Juraska",
                      role = c("aut", "cre"),
                      email = "mjuraska@fredhutch.org"),
               person(given = c("with", "contributions", "from", "Peter", "B."),
                      family = "Gilbert",
                      role = "aut",
                      email = "pgilbert@

Dependency Network

Dependencies Reverse dependencies leaps survival speff2trial

Version History

new 1.0.5 Mar 9, 2026