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rpact

Confirmatory Adaptive Clinical Trial Design and Analysis

v4.4.0 · Mar 4, 2026 · LGPL-3

Description

Design and analysis of confirmatory adaptive clinical trials with continuous, binary, and survival endpoints according to the methods described in the monograph by Wassmer and Brannath (2025) <doi:10.1007/978-3-031-89669-9>. This includes classical group sequential as well as multi-stage adaptive hypotheses tests that are based on the combination testing principle.

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CRAN Check Status

3 NOTE
11 OK
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r-devel-linux-x86_64-debian-clang OK
r-devel-linux-x86_64-debian-gcc OK
r-devel-linux-x86_64-fedora-clang OK
r-devel-linux-x86_64-fedora-gcc OK
r-devel-macos-arm64 OK
r-devel-windows-x86_64 OK
r-oldrel-macos-arm64 NOTE
r-oldrel-macos-x86_64 NOTE
r-oldrel-windows-x86_64 NOTE
r-patched-linux-x86_64 OK
r-release-linux-x86_64 OK
r-release-macos-arm64 OK
r-release-macos-x86_64 OK
r-release-windows-x86_64 OK
Check details (14 non-OK)
OK r-devel-linux-x86_64-debian-clang

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OK r-devel-linux-x86_64-debian-gcc

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OK r-devel-linux-x86_64-fedora-clang

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OK r-devel-linux-x86_64-fedora-gcc

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OK r-devel-macos-arm64

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OK r-devel-windows-x86_64

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NOTE r-oldrel-macos-arm64

installed package size

  installed size is 15.9Mb
  sub-directories of 1Mb or more:
    R      5.1Mb
    help   1.1Mb
    libs   9.6Mb
NOTE r-oldrel-macos-x86_64

installed package size

  installed size is 14.8Mb
  sub-directories of 1Mb or more:
    R      5.0Mb
    help   1.1Mb
    libs   8.5Mb
NOTE r-oldrel-windows-x86_64

installed package size

  installed size is  7.8Mb
  sub-directories of 1Mb or more:
    R      4.9Mb
    help   1.1Mb
    libs   1.6Mb
OK r-patched-linux-x86_64

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OK r-release-linux-x86_64

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OK r-release-macos-arm64

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OK r-release-macos-x86_64

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OK r-release-windows-x86_64

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Check History

NOTE 11 OK · 3 NOTE · 0 WARNING · 0 ERROR · 0 FAILURE Mar 9, 2026
NOTE r-oldrel-macos-arm64

installed package size

  installed size is 15.9Mb
  sub-directories of 1Mb or more:
    R      5.1Mb
    help   1.1Mb
    libs   9.6Mb
NOTE r-oldrel-macos-x86_64

installed package size

  installed size is 14.8Mb
  sub-directories of 1Mb or more:
    R      5.0Mb
    help   1.1Mb
    libs   8.5Mb
NOTE r-oldrel-windows-x86_64

installed package size

  installed size is  7.8Mb
  sub-directories of 1Mb or more:
    R      4.9Mb
    help   1.1Mb
    libs   1.6Mb

Reverse Dependencies (6)

Dependency Network

Dependencies Reverse dependencies rlang R6 knitr Rcpp DTEAssurance TrialSimulator confidenceSim adoptr eventTrack simIDM rpact

Version History

new 4.4.0 Mar 10, 2026