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regmedint

Regression-Based Causal Mediation Analysis with Interaction and Effect Modification Terms

v1.0.2 · Mar 6, 2026 · GPL-2

Description

This is an extension of the regression-based causal mediation analysis first proposed by Valeri and VanderWeele (2013) <doi:10.1037/a0031034> and Valeri and VanderWeele (2015) <doi:10.1097/EDE.0000000000000253>). It supports including effect measure modification by covariates(treatment-covariate and mediator-covariate product terms in mediator and outcome regression models) as proposed by Li et al (2023) <doi:10.1097/EDE.0000000000001643>. It also accommodates the original 'SAS' macro and 'PROC CAUSALMED' procedure in 'SAS' when there is no effect measure modification. Linear and logistic models are supported for the mediator model. Linear, logistic, loglinear, Poisson, negative binomial, Cox, and accelerated failure time (exponential and Weibull) models are supported for the outcome model.

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Check History

OK 11 OK · 0 NOTE · 0 WARNING · 0 ERROR · 0 FAILURE Mar 9, 2026

Dependency Network

Dependencies Reverse dependencies Deriv MASS Matrix assertthat sandwich survival regmedint

Version History

new 1.0.2 Mar 9, 2026