rPBK
Inference and Prediction of Generic Physiologically-Based Kinetic Models
Description
Fit and simulate any kind of physiologically-based kinetic ('PBK') models whatever the number of compartments. Moreover, it allows to account for any link between pairs of compartments, as well as any link of each of the compartments with the external medium. Such generic PBK models have today applications in pharmacology (PBPK models) to describe drug effects, in toxicology and ecotoxicology (PBTK models) to describe chemical substance effects. In case of exposure to a parent compound (drug or chemical) the 'rPBK' package allows to consider metabolites, whatever their number and their phase (I, II, ...). Last but not least, package 'rPBK' can also be used for dynamic flux balance analysis (dFBA) to deal with metabolic networks. See also Charles et al. (2022) <doi:10.1101/2022.04.29.490045>.
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| r-devel-linux-x86_64-debian-clang | OK |
| r-devel-linux-x86_64-debian-gcc | OK |
| r-devel-linux-x86_64-fedora-clang | NOTE |
| r-devel-linux-x86_64-fedora-gcc | NOTE |
| r-devel-macos-arm64 | OK |
| r-devel-windows-x86_64 | OK |
| r-oldrel-macos-arm64 | NOTE |
| r-oldrel-macos-x86_64 | NOTE |
| r-oldrel-windows-x86_64 | NOTE |
| r-patched-linux-x86_64 | OK |
| r-release-linux-x86_64 | OK |
| r-release-macos-arm64 | OK |
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| r-release-windows-x86_64 | OK |
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dependencies in R code
Namespace in Imports field not imported from: ‘rstantools’ All declared Imports should be used.
dependencies in R code
Namespace in Imports field not imported from: ‘rstantools’ All declared Imports should be used.
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for GNU extensions in Makefiles
GNU make is a SystemRequirements.
installed package size
installed size is 88.8Mb
sub-directories of 1Mb or more:
libs 87.7Mb
for GNU extensions in Makefiles
GNU make is a SystemRequirements.
installed package size
installed size is 90.8Mb
sub-directories of 1Mb or more:
libs 89.6Mb
for GNU extensions in Makefiles
GNU make is a SystemRequirements.
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NOTE 9 OK · 5 NOTE · 0 WARNING · 0 ERROR · 0 FAILURE Mar 9, 2026
dependencies in R code
Namespace in Imports field not imported from: ‘rstantools’ All declared Imports should be used.
dependencies in R code
Namespace in Imports field not imported from: ‘rstantools’ All declared Imports should be used.
installed package size
installed size is 88.8Mb
sub-directories of 1Mb or more:
libs 87.7Mb
installed package size
installed size is 90.8Mb
sub-directories of 1Mb or more:
libs 89.6Mb
for GNU extensions in Makefiles
GNU make is a SystemRequirements.