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psme

Penalized Splines Mixed-Effects Models

v1.0.0 · Oct 9, 2025 · GPL-3

Description

Fit penalized splines mixed-effects models (a special case of additive models) for large longitudinal datasets. The package includes a psme() function that (1) relies on package 'mgcv' for constructing population and subject smooth functions as penalized splines, (2) transforms the constructed additive model to a linear mixed-effects model, (3) exploits package 'lme4' for model estimation and (4) backtransforms the estimated linear mixed-effects model to the additive model for interpretation and visualization. See Pedersen et al. (2019) <doi:10.7717/peerj.6876> and Bates et al. (2015) <doi:10.18637/jss.v067.i01> for an introduction. Unlike the gamm() function in 'mgcv', the psme() function is fast and memory-efficient, able to handle datasets with millions of observations.

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OK 14 OK · 0 NOTE · 0 WARNING · 0 ERROR · 0 FAILURE Mar 9, 2026

Dependency Network

Dependencies Reverse dependencies Matrix mgcv lme4 psme

Version History

new 1.0.0 Mar 10, 2026