nonmem2rx

Description

'NONMEM' has been a tool for running nonlinear mixed effects models since the 80s and is still used today (Bauer 2019 <doi:10.1002/psp4.12404>). This tool allows you to convert 'NONMEM' models to 'rxode2' (Wang, Hallow and James (2016) <doi:10.1002/psp4.12052>) and with simple models 'nlmixr2' syntax (Fidler et al (2019) <doi:10.1002/psp4.12445>). The 'nlmixr2' syntax requires the residual specification to be included and it is not always translated. If available, the 'rxode2' model will read in the 'NONMEM' data and compare the simulation for the population model ('PRED') individual model ('IPRED') and residual model ('IWRES') to immediately show how well the translation is performing. This saves the model development time for people who are creating an 'rxode2' model manually. Additionally, this package reads in all the information to allow simulation with uncertainty (that is the number of observations, the number of subjects, and the covariance matrix) with a 'rxode2' model. This is complementary to the 'babelmixr2' package that translates 'nlmixr2' models to 'NONMEM' and can convert the objects converted from 'nonmem2rx' to a full 'nlmixr2' fit.

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  installed size is  9.2Mb
  sub-directories of 1Mb or more:
    libs   5.2Mb
    mods   3.3Mb

  installed size is  9.6Mb
  sub-directories of 1Mb or more:
    libs   5.5Mb
    mods   3.4Mb

  installed size is  6.6Mb
  sub-directories of 1Mb or more:
    libs   2.6Mb
    mods   3.3Mb

Check History

  installed size is  9.2Mb
  sub-directories of 1Mb or more:
    libs   5.2Mb
    mods   3.3Mb

  installed size is  9.6Mb
  sub-directories of 1Mb or more:
    libs   5.5Mb
    mods   3.4Mb

  installed size is  6.6Mb
  sub-directories of 1Mb or more:
    libs   2.6Mb
    mods   3.3Mb

Reverse Dependencies (2)

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