dtpcrm

Dose Transition Pathways for Continual Reassessment Method

v0.1.1 · Aug 20, 2019 · GPL (>= 2)

Description

Provides the dose transition pathways (DTP) to project in advance the doses recommended by a model-based design for subsequent patients (stay, escalate, deescalate or stop early) using all the accumulated toxicity information; See Yap et al (2017) <doi: 10.1158/1078-0432.CCR-17-0582>. DTP can be used as a design and an operational tool and can be displayed as a table or flow diagram. The 'dtpcrm' package also provides the modified continual reassessment method (CRM) and time-to-event CRM (TITE-CRM) with added practical considerations to allow stopping early when there is sufficient evidence that the lowest dose is too toxic and/or there is a sufficient number of patients dosed at the maximum tolerated dose.

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14 NOTE

Show all 14 flavors

Flavor	Status	Time
r-devel-linux-x86_64-debian-clang	NOTE	55.1s
r-devel-linux-x86_64-debian-gcc	NOTE	39.8s
r-devel-linux-x86_64-fedora-clang	NOTE	90.9s
r-devel-linux-x86_64-fedora-gcc	NOTE	103.2s
r-devel-macos-arm64	NOTE	22s
r-devel-windows-x86_64	NOTE	106s
r-oldrel-macos-arm64	NOTE
r-oldrel-macos-x86_64	NOTE	53s
r-oldrel-windows-x86_64	NOTE	129s
r-patched-linux-x86_64	NOTE	52.8s
r-release-linux-x86_64	NOTE	52.5s
r-release-macos-arm64	NOTE
r-release-macos-x86_64	NOTE	69s
r-release-windows-x86_64	NOTE	104s

Check details (17 non-OK)

NOTE r-devel-linux-x86_64-debian-clang

Rd files

checkRd: (-1) applied_crm.Rd:64: Lost braces; missing escapes or markup?
    64 | The empiric model is specified as F(d, beta) = d^{exp(beta)}. The logistic model is
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NOTE r-devel-linux-x86_64-debian-gcc

Rd files

checkRd: (-1) applied_crm.Rd:64: Lost braces; missing escapes or markup?
    64 | The empiric model is specified as F(d, beta) = d^{exp(beta)}. The logistic model is
       |                                                  ^

NOTE r-devel-linux-x86_64-fedora-clang

Rd files

checkRd: (-1) applied_crm.Rd:64: Lost braces; missing escapes or markup?
    64 | The empiric model is specified as F(d, beta) = d^{exp(beta)}. The logistic model is
       |                                                  ^

NOTE r-devel-linux-x86_64-fedora-gcc

Rd files

checkRd: (-1) applied_crm.Rd:64: Lost braces; missing escapes or markup?
    64 | The empiric model is specified as F(d, beta) = d^{exp(beta)}. The logistic model is
       |                                                  ^

NOTE r-devel-macos-arm64

Rd files

checkRd: (-1) applied_crm.Rd:64: Lost braces; missing escapes or markup?
    64 | The empiric model is specified as F(d, beta) = d^{exp(beta)}. The logistic model is
       |                                                  ^

NOTE r-devel-windows-x86_64

Rd files

checkRd: (-1) applied_crm.Rd:64: Lost braces; missing escapes or markup?
    64 | The empiric model is specified as F(d, beta) = d^{exp(beta)}. The logistic model is
       |                                                  ^

NOTE r-oldrel-macos-arm64

LazyData

  'LazyData' is specified without a 'data' directory

NOTE r-oldrel-macos-arm64

Rd files

checkRd: (-1) applied_crm.Rd:64: Lost braces; missing escapes or markup?
    64 | The empiric model is specified as F(d, beta) = d^{exp(beta)}. The logistic model is
       |                                                  ^

NOTE r-oldrel-macos-x86_64

LazyData

  'LazyData' is specified without a 'data' directory

NOTE r-oldrel-macos-x86_64

Rd files

checkRd: (-1) applied_crm.Rd:64: Lost braces; missing escapes or markup?
    64 | The empiric model is specified as F(d, beta) = d^{exp(beta)}. The logistic model is
       |                                                  ^

NOTE r-oldrel-windows-x86_64

LazyData

  'LazyData' is specified without a 'data' directory

NOTE r-oldrel-windows-x86_64

Rd files

checkRd: (-1) applied_crm.Rd:64: Lost braces; missing escapes or markup?
    64 | The empiric model is specified as F(d, beta) = d^{exp(beta)}. The logistic model is
       |                                                  ^

NOTE r-patched-linux-x86_64

Rd files

checkRd: (-1) applied_crm.Rd:64: Lost braces; missing escapes or markup?
    64 | The empiric model is specified as F(d, beta) = d^{exp(beta)}. The logistic model is
       |                                                  ^

NOTE r-release-linux-x86_64

Rd files

checkRd: (-1) applied_crm.Rd:64: Lost braces; missing escapes or markup?
    64 | The empiric model is specified as F(d, beta) = d^{exp(beta)}. The logistic model is
       |                                                  ^

NOTE r-release-macos-arm64

Rd files

checkRd: (-1) applied_crm.Rd:64: Lost braces; missing escapes or markup?
    64 | The empiric model is specified as F(d, beta) = d^{exp(beta)}. The logistic model is
       |                                                  ^

NOTE r-release-macos-x86_64

Rd files

checkRd: (-1) applied_crm.Rd:64: Lost braces; missing escapes or markup?
    64 | The empiric model is specified as F(d, beta) = d^{exp(beta)}. The logistic model is
       |                                                  ^

NOTE r-release-windows-x86_64

Rd files

checkRd: (-1) applied_crm.Rd:64: Lost braces; missing escapes or markup?
    64 | The empiric model is specified as F(d, beta) = d^{exp(beta)}. The logistic model is
       |                                                  ^

Check History

NOTE 0 OK · 14 NOTE · 0 WARNING · 0 ERROR · 0 FAILURE Mar 9, 2026

NOTE r-devel-linux-x86_64-debian-clang

Rd files

checkRd: (-1) applied_crm.Rd:64: Lost braces; missing escapes or markup?
    64 | The empiric model is specified as F(d, beta) = d^{exp(beta)}. The logistic model is
       |                                                  ^

NOTE r-devel-linux-x86_64-debian-gcc

Rd files

checkRd: (-1) applied_crm.Rd:64: Lost braces; missing escapes or markup?
    64 | The empiric model is specified as F(d, beta) = d^{exp(beta)}. The logistic model is
       |                                                  ^

NOTE r-devel-linux-x86_64-fedora-clang

Rd files

checkRd: (-1) applied_crm.Rd:64: Lost braces; missing escapes or markup?
    64 | The empiric model is specified as F(d, beta) = d^{exp(beta)}. The logistic model is
       |                                                  ^

NOTE r-devel-linux-x86_64-fedora-gcc

Rd files

checkRd: (-1) applied_crm.Rd:64: Lost braces; missing escapes or markup?
    64 | The empiric model is specified as F(d, beta) = d^{exp(beta)}. The logistic model is
       |                                                  ^

NOTE r-devel-macos-arm64

Rd files

checkRd: (-1) applied_crm.Rd:64: Lost braces; missing escapes or markup?
    64 | The empiric model is specified as F(d, beta) = d^{exp(beta)}. The logistic model is
       |                                                  ^

NOTE r-devel-windows-x86_64

Rd files

checkRd: (-1) applied_crm.Rd:64: Lost braces; missing escapes or markup?
    64 | The empiric model is specified as F(d, beta) = d^{exp(beta)}. The logistic model is
       |                                                  ^

NOTE r-patched-linux-x86_64

Rd files

checkRd: (-1) applied_crm.Rd:64: Lost braces; missing escapes or markup?
    64 | The empiric model is specified as F(d, beta) = d^{exp(beta)}. The logistic model is
       |                                                  ^

NOTE r-release-linux-x86_64

Rd files

checkRd: (-1) applied_crm.Rd:64: Lost braces; missing escapes or markup?
    64 | The empiric model is specified as F(d, beta) = d^{exp(beta)}. The logistic model is
       |                                                  ^

NOTE r-release-macos-arm64

Rd files

checkRd: (-1) applied_crm.Rd:64: Lost braces; missing escapes or markup?
    64 | The empiric model is specified as F(d, beta) = d^{exp(beta)}. The logistic model is
       |                                                  ^

NOTE r-release-macos-x86_64

Rd files

checkRd: (-1) applied_crm.Rd:64: Lost braces; missing escapes or markup?
    64 | The empiric model is specified as F(d, beta) = d^{exp(beta)}. The logistic model is
       |                                                  ^

NOTE r-release-windows-x86_64

Rd files

checkRd: (-1) applied_crm.Rd:64: Lost braces; missing escapes or markup?
    64 | The empiric model is specified as F(d, beta) = d^{exp(beta)}. The logistic model is
       |                                                  ^

NOTE r-oldrel-macos-arm64

Rd files

checkRd: (-1) applied_crm.Rd:64: Lost braces; missing escapes or markup?
    64 | The empiric model is specified as F(d, beta) = d^{exp(beta)}. The logistic model is
       |                                                  ^

NOTE r-oldrel-macos-x86_64

Rd files

checkRd: (-1) applied_crm.Rd:64: Lost braces; missing escapes or markup?
    64 | The empiric model is specified as F(d, beta) = d^{exp(beta)}. The logistic model is
       |                                                  ^

NOTE r-oldrel-windows-x86_64

Rd files

checkRd: (-1) applied_crm.Rd:64: Lost braces; missing escapes or markup?
    64 | The empiric model is specified as F(d, beta) = d^{exp(beta)}. The logistic model is
       |                                                  ^

Dependency Network

Version History

new 0.1.1 Mar 9, 2026