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dowser

B Cell Receptor Phylogenetics Toolkit

v2.4.0 · Oct 14, 2025 · AGPL-3

Description

Provides a set of functions for inferring, visualizing, and analyzing B cell phylogenetic trees. Provides methods to 1) reconstruct unmutated ancestral sequences, 2) build B cell phylogenetic trees using multiple methods, 3) visualize trees with metadata at the tips, 4) reconstruct intermediate sequences, 5) detect biased ancestor-descendant relationships among metadata types Workflow examples available at documentation site (see URL). Citations: Hoehn et al (2022) <doi:10.1371/journal.pcbi.1009885>, Hoehn et al (2021) <doi:10.1101/2021.01.06.425648>.

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CRAN Check Status

5 ERROR
9 OK
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r-devel-linux-x86_64-debian-clang ERROR
r-devel-linux-x86_64-debian-gcc ERROR
r-devel-linux-x86_64-fedora-clang ERROR
r-devel-linux-x86_64-fedora-gcc ERROR
r-devel-macos-arm64 OK
r-devel-windows-x86_64 OK
r-oldrel-macos-arm64 OK
r-oldrel-macos-x86_64 ERROR
r-oldrel-windows-x86_64 OK
r-patched-linux-x86_64 OK
r-release-linux-x86_64 OK
r-release-macos-arm64 OK
r-release-macos-x86_64 OK
r-release-windows-x86_64 OK
Check details (17 non-OK)
NOTE r-devel-linux-x86_64-debian-clang

CRAN incoming feasibility

Maintainer: ‘Kenneth Hoehn <kenneth.b.hoehn@dartmouth.edu>’

Found the following (possibly) invalid file URIs:
  URI: Resolve-Light-Chains-Vignette.md
    From: inst/doc/Building-Trees-Vignette.pdf
  URI: Plotting-Trees-Vignette.md
    From: inst/doc/Measurable-Evolution.pdf
  URI: Building-Trees-Vignette.md
    From: inst/doc/Resolve-Light-Chains-Vignette.pdf
ERROR r-devel-linux-x86_64-debian-clang

package dependencies

Packages required but not available: 'alakazam', 'Biostrings', 'shazam'

Package suggested but not available for checking: ‘pwalign’

See section ‘The DESCRIPTION file’ in the ‘Writing R Extensions’
manual.
NOTE r-devel-linux-x86_64-debian-gcc

CRAN incoming feasibility

Maintainer: ‘Kenneth Hoehn <kenneth.b.hoehn@dartmouth.edu>’

Found the following (possibly) invalid file URIs:
  URI: Resolve-Light-Chains-Vignette.md
    From: inst/doc/Building-Trees-Vignette.pdf
  URI: Plotting-Trees-Vignette.md
    From: inst/doc/Measurable-Evolution.pdf
  URI: Building-Trees-Vignette.md
    From: inst/doc/Resolve-Light-Chains-Vignette.pdf
ERROR r-devel-linux-x86_64-debian-gcc

whether package can be installed

Installation failed.
See ‘/home/hornik/tmp/R.check/r-devel-gcc/Work/PKGS/dowser.Rcheck/00install.out’ for details.
ERROR r-devel-linux-x86_64-fedora-clang

whether package can be installed

Installation failed.
See ‘/data/gannet/ripley/R/packages/tests-clang/dowser.Rcheck/00install.out’ for details.
ERROR r-devel-linux-x86_64-fedora-gcc

whether package can be installed

Installation failed.
See ‘/data/gannet/ripley/R/packages/tests-devel/dowser.Rcheck/00install.out’ for details.
OK r-devel-macos-arm64

*


            
OK r-devel-windows-x86_64

*


            
OK r-oldrel-macos-arm64

*


            
ERROR r-oldrel-macos-x86_64

examples

Running examples in ‘dowser-Ex.R’ failed
The error most likely occurred in:

> ### Name: maskCodons
> ### Title: 'maskCodons' Masks codons split by insertions
> ### Aliases: maskCodons
> 
> ### ** Examples
> 
> s = "ATCATCATC..."
> q = "ATCTTTATCATC"
> print(maskCodons(1,q,s,TRUE))
Error in loadNamespace(x) : there is no package called ‘pwalign’
Calls: print ... loadNamespace -> withRestarts -> withOneRestart -> doWithOneRestart
Execution halted
NOTE r-oldrel-macos-x86_64

package dependencies

Package suggested but not available for checking: ‘pwalign’
OK r-oldrel-windows-x86_64

*


            
OK r-patched-linux-x86_64

*


            
OK r-release-linux-x86_64

*


            
OK r-release-macos-arm64

*


            
OK r-release-macos-x86_64

*


            
OK r-release-windows-x86_64

*


            

Check History

ERROR 9 OK · 0 NOTE · 0 WARNING · 5 ERROR · 0 FAILURE Mar 9, 2026
ERROR r-devel-linux-x86_64-debian-clang

CRAN incoming feasibility

Maintainer: ‘Kenneth Hoehn <kenneth.b.hoehn@dartmouth.edu>’

Found the following (possibly) invalid file URIs:
  URI: Resolve-Light-Chains-Vignette.md
    From: inst/doc/Building-Trees-Vignette.pdf
  URI: Plotting-Trees-Vignette.md
    From: inst/doc/Measurable-Evolution.pdf
  URI: Building-Trees-Vignette.md
    From: inst/doc/Resolve-Light-Chains-Vignette.pdf
ERROR r-devel-linux-x86_64-debian-gcc

CRAN incoming feasibility

Maintainer: ‘Kenneth Hoehn <kenneth.b.hoehn@dartmouth.edu>’

Found the following (possibly) invalid file URIs:
  URI: Resolve-Light-Chains-Vignette.md
    From: inst/doc/Building-Trees-Vignette.pdf
  URI: Plotting-Trees-Vignette.md
    From: inst/doc/Measurable-Evolution.pdf
  URI: Building-Trees-Vignette.md
    From: inst/doc/Resolve-Light-Chains-Vignette.pdf
ERROR r-devel-linux-x86_64-fedora-clang

whether package can be installed

Installation failed.
See ‘/data/gannet/ripley/R/packages/tests-clang/dowser.Rcheck/00install.out’ for details.
ERROR r-devel-linux-x86_64-fedora-gcc

whether package can be installed

Installation failed.
See ‘/data/gannet/ripley/R/packages/tests-devel/dowser.Rcheck/00install.out’ for details.
ERROR r-oldrel-macos-x86_64

package dependencies

Package suggested but not available for checking: ‘pwalign’

Dependency Network

Dependencies Reverse dependencies ggplot2 airr alakazam ape Biostrings dplyr (>= 1.0) ggtree gridExtra markdown phangorn phylotate RColorBrewer rlang shazam stringr +3 more dependencies dowser

Version History

new 2.4.0 Mar 9, 2026