ceas

Cellular Energetics Analysis Software

v1.3.0 · Dec 20, 2024 · MIT + file LICENSE

Description

Measuring cellular energetics is essential to understanding a matrix’s (e.g. cell, tissue or biofluid) metabolic state. The Agilent Seahorse machine is a common method to measure real-time cellular energetics, but existing analysis tools are highly manual or lack functionality. The Cellular Energetics Analysis Software (ceas) R package fills this analytical gap by providing modular and automated Seahorse data analysis and visualization using the methods described by Mookerjee et al. (2017) <doi:10.1074/jbc.m116.774471>.

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CRAN Check Status

1 ERROR

11 NOTE

2 OK

Show all 14 flavors

Flavor	Status	Time
r-devel-linux-x86_64-debian-clang	NOTE	165.4s
r-devel-linux-x86_64-debian-gcc	NOTE	109.7s
r-devel-linux-x86_64-fedora-clang	NOTE	255.9s
r-devel-linux-x86_64-fedora-gcc	NOTE	255.5s
r-devel-macos-arm64	NOTE	40s
r-devel-windows-x86_64	NOTE	151s
r-oldrel-macos-arm64	OK
r-oldrel-macos-x86_64	OK	123s
r-oldrel-windows-x86_64	ERROR	208s
r-patched-linux-x86_64	NOTE	146.8s
r-release-linux-x86_64	NOTE	145.2s
r-release-macos-arm64	NOTE
r-release-macos-x86_64	NOTE	126s
r-release-windows-x86_64	NOTE	151s

Check details (14 non-OK)

NOTE r-devel-linux-x86_64-debian-clang

DESCRIPTION meta-information

  Missing dependency on R >= 4.1.0 because package code uses the pipe
  |> or function shorthand \(...) syntax added in R 4.1.0.
  File(s) using such syntax:
    ‘atp_plot.Rd’ ‘bioscope_plot.Rd’ ‘energetics_lme_summary.Rd’
    ‘energetics_ols_summary.Rd’ ‘fit_lme.Rd’ ‘get_energetics.Rd’
    ‘get_energetics_summary.Rd’ ‘get_rate_summary.Rd’
    ‘make_bioscope_plot.Rd’ ‘normalize.Rd’ ‘partition_data.Rd’
    ‘pipelines.r’ ‘rate_plot.R’ ‘rate_plot.Rd’ ‘rates_lme_summary.Rd’
    ‘read_data.Rd’

NOTE r-devel-linux-x86_64-debian-gcc

DESCRIPTION meta-information

  Missing dependency on R >= 4.1.0 because package code uses the pipe
  |> or function shorthand \(...) syntax added in R 4.1.0.
  File(s) using such syntax:
    ‘atp_plot.Rd’ ‘bioscope_plot.Rd’ ‘energetics_lme_summary.Rd’
    ‘energetics_ols_summary.Rd’ ‘fit_lme.Rd’ ‘get_energetics.Rd’
    ‘get_energetics_summary.Rd’ ‘get_rate_summary.Rd’
    ‘make_bioscope_plot.Rd’ ‘normalize.Rd’ ‘partition_data.Rd’
    ‘pipelines.r’ ‘rate_plot.R’ ‘rate_plot.Rd’ ‘rates_lme_summary.Rd’
    ‘read_data.Rd’

NOTE r-devel-linux-x86_64-fedora-clang

DESCRIPTION meta-information

  Missing dependency on R >= 4.1.0 because package code uses the pipe
  |> or function shorthand \(...) syntax added in R 4.1.0.
  File(s) using such syntax:
    ‘atp_plot.Rd’ ‘bioscope_plot.Rd’ ‘energetics_lme_summary.Rd’
    ‘energetics_ols_summary.Rd’ ‘fit_lme.Rd’ ‘get_energetics.Rd’
    ‘get_energetics_summary.Rd’ ‘get_rate_summary.Rd’
    ‘make_bioscope_plot.Rd’ ‘normalize.Rd’ ‘partition_data.Rd’
    ‘pipelines.r’ ‘rate_plot.R’ ‘rate_plot.Rd’ ‘rates_lme_summary.Rd’
    ‘read_data.Rd’

NOTE r-devel-linux-x86_64-fedora-gcc

DESCRIPTION meta-information

  Missing dependency on R >= 4.1.0 because package code uses the pipe
  |> or function shorthand \(...) syntax added in R 4.1.0.
  File(s) using such syntax:
    ‘atp_plot.Rd’ ‘bioscope_plot.Rd’ ‘energetics_lme_summary.Rd’
    ‘energetics_ols_summary.Rd’ ‘fit_lme.Rd’ ‘get_energetics.Rd’
    ‘get_energetics_summary.Rd’ ‘get_rate_summary.Rd’
    ‘make_bioscope_plot.Rd’ ‘normalize.Rd’ ‘partition_data.Rd’
    ‘pipelines.r’ ‘rate_plot.R’ ‘rate_plot.Rd’ ‘rates_lme_summary.Rd’
    ‘read_data.Rd’

NOTE r-devel-macos-arm64

DESCRIPTION meta-information

  Missing dependency on R >= 4.1.0 because package code uses the pipe
  |> or function shorthand \(...) syntax added in R 4.1.0.
  File(s) using such syntax:
    ‘atp_plot.Rd’ ‘bioscope_plot.Rd’ ‘energetics_lme_summary.Rd’
    ‘energetics_ols_summary.Rd’ ‘fit_lme.Rd’ ‘get_energetics.Rd’
    ‘get_energetics_summary.Rd’ ‘get_rate_summary.Rd’
    ‘make_bioscope_plot.Rd’ ‘normalize.Rd’ ‘partition_data.Rd’
    ‘pipelines.r’ ‘rate_plot.R’ ‘rate_plot.Rd’ ‘rates_lme_summary.Rd’
    ‘read_data.Rd’

NOTE r-devel-windows-x86_64

DESCRIPTION meta-information

  Missing dependency on R >= 4.1.0 because package code uses the pipe
  |> or function shorthand \(...) syntax added in R 4.1.0.
  File(s) using such syntax:
    'atp_plot.Rd' 'bioscope_plot.Rd' 'energetics_lme_summary.Rd'
    'energetics_ols_summary.Rd' 'fit_lme.Rd' 'get_energetics.Rd'
    'get_energetics_summary.Rd' 'get_rate_summary.Rd'
    'make_bioscope_plot.Rd' 'normalize.Rd' 'partition_data.Rd'
    'pipelines.r' 'rate_plot.R' 'rate_plot.Rd' 'rates_lme_summary.Rd'
    'read_data.Rd'

OK r-oldrel-macos-arm64

OK r-oldrel-macos-x86_64

ERROR r-oldrel-windows-x86_64

re-building of vignette outputs

Error(s) in re-building vignettes:
--- re-building 'atp_calculation.Rmd' using rmarkdown
File mito_glyco_tests.png not found in resource path
Error: processing vignette 'atp_calculation.Rmd' failed with diagnostics:
pandoc document conversion failed with error 99
--- failed re-building 'atp_calculation.Rmd'

--- re-building 'ceas.Rmd' using rmarkdown
--- finished re-building 'ceas.Rmd'

SUMMARY: processing the following file failed:
  'atp_calculation.Rmd'

Error: Vignette re-building failed.
Execution halted

NOTE r-patched-linux-x86_64

DESCRIPTION meta-information

  Missing dependency on R >= 4.1.0 because package code uses the pipe
  |> or function shorthand \(...) syntax added in R 4.1.0.
  File(s) using such syntax:
    ‘atp_plot.Rd’ ‘bioscope_plot.Rd’ ‘energetics_lme_summary.Rd’
    ‘energetics_ols_summary.Rd’ ‘fit_lme.Rd’ ‘get_energetics.Rd’
    ‘get_energetics_summary.Rd’ ‘get_rate_summary.Rd’
    ‘make_bioscope_plot.Rd’ ‘normalize.Rd’ ‘partition_data.Rd’
    ‘pipelines.r’ ‘rate_plot.R’ ‘rate_plot.Rd’ ‘rates_lme_summary.Rd’
    ‘read_data.Rd’

NOTE r-release-linux-x86_64

DESCRIPTION meta-information

  Missing dependency on R >= 4.1.0 because package code uses the pipe
  |> or function shorthand \(...) syntax added in R 4.1.0.
  File(s) using such syntax:
    ‘atp_plot.Rd’ ‘bioscope_plot.Rd’ ‘energetics_lme_summary.Rd’
    ‘energetics_ols_summary.Rd’ ‘fit_lme.Rd’ ‘get_energetics.Rd’
    ‘get_energetics_summary.Rd’ ‘get_rate_summary.Rd’
    ‘make_bioscope_plot.Rd’ ‘normalize.Rd’ ‘partition_data.Rd’
    ‘pipelines.r’ ‘rate_plot.R’ ‘rate_plot.Rd’ ‘rates_lme_summary.Rd’
    ‘read_data.Rd’

NOTE r-release-macos-arm64

DESCRIPTION meta-information

  Missing dependency on R >= 4.1.0 because package code uses the pipe
  |> or function shorthand \(...) syntax added in R 4.1.0.
  File(s) using such syntax:
    ‘atp_plot.Rd’ ‘bioscope_plot.Rd’ ‘energetics_lme_summary.Rd’
    ‘energetics_ols_summary.Rd’ ‘fit_lme.Rd’ ‘get_energetics.Rd’
    ‘get_energetics_summary.Rd’ ‘get_rate_summary.Rd’
    ‘make_bioscope_plot.Rd’ ‘normalize.Rd’ ‘partition_data.Rd’
    ‘pipelines.r’ ‘rate_plot.R’ ‘rate_plot.Rd’ ‘rates_lme_summary.Rd’
    ‘read_data.Rd’

NOTE r-release-macos-x86_64

DESCRIPTION meta-information

  Missing dependency on R >= 4.1.0 because package code uses the pipe
  |> or function shorthand \(...) syntax added in R 4.1.0.
  File(s) using such syntax:
    ‘atp_plot.Rd’ ‘bioscope_plot.Rd’ ‘energetics_lme_summary.Rd’
    ‘energetics_ols_summary.Rd’ ‘fit_lme.Rd’ ‘get_energetics.Rd’
    ‘get_energetics_summary.Rd’ ‘get_rate_summary.Rd’
    ‘make_bioscope_plot.Rd’ ‘normalize.Rd’ ‘partition_data.Rd’
    ‘pipelines.r’ ‘rate_plot.R’ ‘rate_plot.Rd’ ‘rates_lme_summary.Rd’
    ‘read_data.Rd’

NOTE r-release-windows-x86_64

DESCRIPTION meta-information

  Missing dependency on R >= 4.1.0 because package code uses the pipe
  |> or function shorthand \(...) syntax added in R 4.1.0.
  File(s) using such syntax:
    'atp_plot.Rd' 'bioscope_plot.Rd' 'energetics_lme_summary.Rd'
    'energetics_ols_summary.Rd' 'fit_lme.Rd' 'get_energetics.Rd'
    'get_energetics_summary.Rd' 'get_rate_summary.Rd'
    'make_bioscope_plot.Rd' 'normalize.Rd' 'partition_data.Rd'
    'pipelines.r' 'rate_plot.R' 'rate_plot.Rd' 'rates_lme_summary.Rd'
    'read_data.Rd'

Check History

ERROR 2 OK · 11 NOTE · 0 WARNING · 1 ERROR · 0 FAILURE Mar 9, 2026

NOTE r-devel-linux-x86_64-debian-clang

DESCRIPTION meta-information

  Missing dependency on R >= 4.1.0 because package code uses the pipe
  |> or function shorthand \(...) syntax added in R 4.1.0.
  File(s) using such syntax:
    ‘atp_plot.Rd’ ‘bioscope_plot.Rd’ ‘energetics_lme_summary.Rd’
    ‘energetics_ols_summary.Rd’ ‘fit_lme.Rd’ ‘get_energetics.Rd’
    ‘get_energetics_summary.Rd’ ‘get_rate_summary.Rd’
    ‘make_bioscope_plot.Rd’ ‘normalize.Rd’ ‘partition_data.Rd’
    ‘pipelines.r’ ‘rate_plot.R’ ‘rate_plot.Rd’ ‘rates_lme_summary.Rd’
    ‘read_data.Rd’

NOTE r-devel-linux-x86_64-debian-gcc

DESCRIPTION meta-information

  Missing dependency on R >= 4.1.0 because package code uses the pipe
  |> or function shorthand \(...) syntax added in R 4.1.0.
  File(s) using such syntax:
    ‘atp_plot.Rd’ ‘bioscope_plot.Rd’ ‘energetics_lme_summary.Rd’
    ‘energetics_ols_summary.Rd’ ‘fit_lme.Rd’ ‘get_energetics.Rd’
    ‘get_energetics_summary.Rd’ ‘get_rate_summary.Rd’
    ‘make_bioscope_plot.Rd’ ‘normalize.Rd’ ‘partition_data.Rd’
    ‘pipelines.r’ ‘rate_plot.R’ ‘rate_plot.Rd’ ‘rates_lme_summary.Rd’
    ‘read_data.Rd’

NOTE r-devel-linux-x86_64-fedora-clang

DESCRIPTION meta-information

  Missing dependency on R >= 4.1.0 because package code uses the pipe
  |> or function shorthand \(...) syntax added in R 4.1.0.
  File(s) using such syntax:
    ‘atp_plot.Rd’ ‘bioscope_plot.Rd’ ‘energetics_lme_summary.Rd’
    ‘energetics_ols_summary.Rd’ ‘fit_lme.Rd’ ‘get_energetics.Rd’
    ‘get_energetics_summary.Rd’ ‘get_rate_summary.Rd’
    ‘make_bioscope_plot.Rd’ ‘normalize.Rd’ ‘partition_data.Rd’
    ‘pipelines.r’ ‘rate_plot.R’ ‘rate_plot.Rd’ ‘rates_lme_summary.Rd’
    ‘read_data.Rd’

NOTE r-devel-linux-x86_64-fedora-gcc

DESCRIPTION meta-information

  Missing dependency on R >= 4.1.0 because package code uses the pipe
  |> or function shorthand \(...) syntax added in R 4.1.0.
  File(s) using such syntax:
    ‘atp_plot.Rd’ ‘bioscope_plot.Rd’ ‘energetics_lme_summary.Rd’
    ‘energetics_ols_summary.Rd’ ‘fit_lme.Rd’ ‘get_energetics.Rd’
    ‘get_energetics_summary.Rd’ ‘get_rate_summary.Rd’
    ‘make_bioscope_plot.Rd’ ‘normalize.Rd’ ‘partition_data.Rd’
    ‘pipelines.r’ ‘rate_plot.R’ ‘rate_plot.Rd’ ‘rates_lme_summary.Rd’
    ‘read_data.Rd’

NOTE r-devel-macos-arm64

DESCRIPTION meta-information

  Missing dependency on R >= 4.1.0 because package code uses the pipe
  |> or function shorthand \(...) syntax added in R 4.1.0.
  File(s) using such syntax:
    ‘atp_plot.Rd’ ‘bioscope_plot.Rd’ ‘energetics_lme_summary.Rd’
    ‘energetics_ols_summary.Rd’ ‘fit_lme.Rd’ ‘get_energetics.Rd’
    ‘get_energetics_summary.Rd’ ‘get_rate_summary.Rd’
    ‘make_bioscope_plot.Rd’ ‘normalize.Rd’ ‘partition_data.Rd’
    ‘pipelines.r’ ‘rate_plot.R’ ‘rate_plot.Rd’ ‘rates_lme_summary.Rd’
    ‘read_data.Rd’

NOTE r-devel-windows-x86_64

DESCRIPTION meta-information

  Missing dependency on R >= 4.1.0 because package code uses the pipe
  |> or function shorthand \(...) syntax added in R 4.1.0.
  File(s) using such syntax:
    'atp_plot.Rd' 'bioscope_plot.Rd' 'energetics_lme_summary.Rd'
    'energetics_ols_summary.Rd' 'fit_lme.Rd' 'get_energetics.Rd'
    'get_energetics_summary.Rd' 'get_rate_summary.Rd'
    'make_bioscope_plot.Rd' 'normalize.Rd' 'partition_data.Rd'
    'pipelines.r' 'rate_plot.R' 'rate_plot.Rd' 'rates_lme_summary.Rd'
    'read_data.Rd'

NOTE r-patched-linux-x86_64

DESCRIPTION meta-information

  Missing dependency on R >= 4.1.0 because package code uses the pipe
  |> or function shorthand \(...) syntax added in R 4.1.0.
  File(s) using such syntax:
    ‘atp_plot.Rd’ ‘bioscope_plot.Rd’ ‘energetics_lme_summary.Rd’
    ‘energetics_ols_summary.Rd’ ‘fit_lme.Rd’ ‘get_energetics.Rd’
    ‘get_energetics_summary.Rd’ ‘get_rate_summary.Rd’
    ‘make_bioscope_plot.Rd’ ‘normalize.Rd’ ‘partition_data.Rd’
    ‘pipelines.r’ ‘rate_plot.R’ ‘rate_plot.Rd’ ‘rates_lme_summary.Rd’
    ‘read_data.Rd’

NOTE r-release-linux-x86_64

DESCRIPTION meta-information

  Missing dependency on R >= 4.1.0 because package code uses the pipe
  |> or function shorthand \(...) syntax added in R 4.1.0.
  File(s) using such syntax:
    ‘atp_plot.Rd’ ‘bioscope_plot.Rd’ ‘energetics_lme_summary.Rd’
    ‘energetics_ols_summary.Rd’ ‘fit_lme.Rd’ ‘get_energetics.Rd’
    ‘get_energetics_summary.Rd’ ‘get_rate_summary.Rd’
    ‘make_bioscope_plot.Rd’ ‘normalize.Rd’ ‘partition_data.Rd’
    ‘pipelines.r’ ‘rate_plot.R’ ‘rate_plot.Rd’ ‘rates_lme_summary.Rd’
    ‘read_data.Rd’

NOTE r-release-macos-arm64

DESCRIPTION meta-information

  Missing dependency on R >= 4.1.0 because package code uses the pipe
  |> or function shorthand \(...) syntax added in R 4.1.0.
  File(s) using such syntax:
    ‘atp_plot.Rd’ ‘bioscope_plot.Rd’ ‘energetics_lme_summary.Rd’
    ‘energetics_ols_summary.Rd’ ‘fit_lme.Rd’ ‘get_energetics.Rd’
    ‘get_energetics_summary.Rd’ ‘get_rate_summary.Rd’
    ‘make_bioscope_plot.Rd’ ‘normalize.Rd’ ‘partition_data.Rd’
    ‘pipelines.r’ ‘rate_plot.R’ ‘rate_plot.Rd’ ‘rates_lme_summary.Rd’
    ‘read_data.Rd’

NOTE r-release-macos-x86_64

DESCRIPTION meta-information

  Missing dependency on R >= 4.1.0 because package code uses the pipe
  |> or function shorthand \(...) syntax added in R 4.1.0.
  File(s) using such syntax:
    ‘atp_plot.Rd’ ‘bioscope_plot.Rd’ ‘energetics_lme_summary.Rd’
    ‘energetics_ols_summary.Rd’ ‘fit_lme.Rd’ ‘get_energetics.Rd’
    ‘get_energetics_summary.Rd’ ‘get_rate_summary.Rd’
    ‘make_bioscope_plot.Rd’ ‘normalize.Rd’ ‘partition_data.Rd’
    ‘pipelines.r’ ‘rate_plot.R’ ‘rate_plot.Rd’ ‘rates_lme_summary.Rd’
    ‘read_data.Rd’

NOTE r-release-windows-x86_64

DESCRIPTION meta-information

  Missing dependency on R >= 4.1.0 because package code uses the pipe
  |> or function shorthand \(...) syntax added in R 4.1.0.
  File(s) using such syntax:
    'atp_plot.Rd' 'bioscope_plot.Rd' 'energetics_lme_summary.Rd'
    'energetics_ols_summary.Rd' 'fit_lme.Rd' 'get_energetics.Rd'
    'get_energetics_summary.Rd' 'get_rate_summary.Rd'
    'make_bioscope_plot.Rd' 'normalize.Rd' 'partition_data.Rd'
    'pipelines.r' 'rate_plot.R' 'rate_plot.Rd' 'rates_lme_summary.Rd'
    'read_data.Rd'

ERROR r-oldrel-windows-x86_64

re-building of vignette outputs

Error(s) in re-building vignettes:
--- re-building 'atp_calculation.Rmd' using rmarkdown
File mito_glyco_tests.png not found in resource path
Error: processing vignette 'atp_calculation.Rmd' failed with diagnostics:
pandoc document conversion failed with error 99
--- failed re-building 'atp_calculation.Rmd'

--- re-building 'ceas.Rmd' using rmarkdown
--- finished re-building 'ceas.Rmd'

SUMMARY: processing the following file failed:
  'atp_calculation.Rmd'

Error: Vignette re-building failed.
Ex

Dependency Network

Version History

new 1.3.0 Mar 9, 2026

Maintainer

Rachel House

Dependencies

Imports

data.table ggplot2 lme4 readxl stats

Suggests

knitr rmarkdown testthat (>= 3.0.0)

Compilation

No compilation needed

First Published

Mar 9, 2026

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CRAN Checks

View on CRAN →