Description
R codes for the (adaptive) Sum of Powered Score ('SPU' and 'aSPU') tests, inverse variance weighted Sum of Powered score ('SPUw' and 'aSPUw') tests and gene-based and some pathway based association tests (Pathway based Sum of Powered Score tests ('SPUpath'), adaptive 'SPUpath' ('aSPUpath') test, 'GEEaSPU' test for multiple traits - single 'SNP' (single nucleotide polymorphism) association in generalized estimation equations, 'MTaSPUs' test for multiple traits - single 'SNP' association with Genome Wide Association Studies ('GWAS') summary statistics, Gene-based Association Test that uses an extended 'Simes' procedure ('GATES'), Hybrid Set-based Test ('HYST') and extended version of 'GATES' test for pathway-based association testing ('GATES-Simes'). ). The tests can be used with genetic and other data sets with covariates. The response variable is binary or quantitative. Summary; (1) Single trait-'SNP' set association with individual-level data ('aSPU', 'aSPUw', 'aSPUr'), (2) Single trait-'SNP' set association with summary statistics ('aSPUs'), (3) Single trait-pathway association with individual-level data ('aSPUpath'), (4) Single trait-pathway association with summary statistics ('aSPUsPath'), (5) Multiple traits-single 'SNP' association with individual-level data ('GEEaSPU'), (6) Multiple traits- single 'SNP' association with summary statistics ('MTaSPUs'), (7) Multiple traits-'SNP' set association with summary statistics('MTaSPUsSet'), (8) Multiple traits-pathway association with summary statistics('MTaSPUsSetPath').
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| Flavor | Status |
|---|---|
| r-devel-linux-x86_64-debian-clang | NOTE |
| r-devel-linux-x86_64-debian-gcc | NOTE |
| r-devel-linux-x86_64-fedora-clang | OK |
| r-devel-linux-x86_64-fedora-gcc | OK |
| r-devel-macos-arm64 | OK |
| r-devel-windows-x86_64 | OK |
| r-oldrel-macos-arm64 | OK |
| r-oldrel-macos-x86_64 | OK |
| r-oldrel-windows-x86_64 | OK |
| r-patched-linux-x86_64 | OK |
| r-release-linux-x86_64 | OK |
| r-release-macos-arm64 | OK |
| r-release-macos-x86_64 | OK |
| r-release-windows-x86_64 | OK |
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CRAN incoming feasibility
Maintainer: ‘Il-Youp Kwak <ikwak2@cau.ac.kr>’
No Authors@R field in DESCRIPTION.
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Authors@R: c(person(given = "Il-Youp",
family = "Kwak",
role = c("aut", "cre"),
email = "ikwak2@cau.ac.kr"),
person(given = c("others", "in", "each", "function"),
family = "manual)",
role = "aut",
comment = "s"))
as necessary.
CRAN incoming feasibility
Maintainer: ‘Il-Youp Kwak <ikwak2@cau.ac.kr>’
No Authors@R field in DESCRIPTION.
Please add one, modifying
Authors@R: c(person(given = "Il-Youp",
family = "Kwak",
role = c("aut", "cre"),
email = "ikwak2@cau.ac.kr"),
person(given = c("others", "in", "each", "function"),
family = "manual)",
role = "aut",
comment = "s"))
as necessary.
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NOTE 12 OK · 2 NOTE · 0 WARNING · 0 ERROR · 0 FAILURE Mar 9, 2026
CRAN incoming feasibility
Maintainer: ‘Il-Youp Kwak <ikwak2@cau.ac.kr>’
No Authors@R field in DESCRIPTION.
Please add one, modifying
Authors@R: c(person(given = "Il-Youp",
family = "Kwak",
role = c("aut", "cre"),
email = "ikwak2@cau.ac.kr"),
person(given = c("others", "in", "each", "function"),
family = "manual)",
role = "aut",
comment = "s"))
as necessary.
CRAN incoming feasibility
Maintainer: ‘Il-Youp Kwak <ikwak2@cau.ac.kr>’
No Authors@R field in DESCRIPTION.
Please add one, modifying
Authors@R: c(person(given = "Il-Youp",
family = "Kwak",
role = c("aut", "cre"),
email = "ikwak2@cau.ac.kr"),
person(given = c("others", "in", "each", "function"),
family = "manual)",
role = "aut",
comment = "s"))
as necessary.