SimDissolution
Modeling and Assessing Similarity of Drug Dissolutions Profiles
Description
Implementation of a model-based bootstrap approach for testing whether two formulations are similar. The package provides a function for fitting a pharmacokinetic model to time-concentration data and comparing the results for all five candidate models regarding the Residual Sum of Squares (RSS). The candidate set contains a First order, Hixson-Crowell, Higuchi, Weibull and a logistic model. The assessment of similarity implemented in this package is performed regarding the maximum deviation of the profiles. See Moellenhoff et al. (2018) <doi:10.1002/sim.7689> for details.
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Show all 14 flavors
| Flavor | Status |
|---|---|
| r-devel-linux-x86_64-debian-clang | NOTE |
| r-devel-linux-x86_64-debian-gcc | NOTE |
| r-devel-linux-x86_64-fedora-clang | OK |
| r-devel-linux-x86_64-fedora-gcc | OK |
| r-devel-macos-arm64 | OK |
| r-devel-windows-x86_64 | OK |
| r-oldrel-macos-arm64 | OK |
| r-oldrel-macos-x86_64 | OK |
| r-oldrel-windows-x86_64 | OK |
| r-patched-linux-x86_64 | OK |
| r-release-linux-x86_64 | OK |
| r-release-macos-arm64 | OK |
| r-release-macos-x86_64 | OK |
| r-release-windows-x86_64 | OK |
Check details (14 non-OK)
CRAN incoming feasibility
Maintainer: ‘Kathrin Moellenhoff <kathrin.moellenhoff@rub.de>’
No Authors@R field in DESCRIPTION.
Please add one, modifying
Authors@R: person(given = "Kathrin",
family = "Moellenhoff",
role = c("aut", "cre"),
email = "kathrin.moellenhoff@rub.de")
as necessary.
CRAN incoming feasibility
Maintainer: ‘Kathrin Moellenhoff <kathrin.moellenhoff@rub.de>’
No Authors@R field in DESCRIPTION.
Please add one, modifying
Authors@R: person(given = "Kathrin",
family = "Moellenhoff",
role = c("aut", "cre"),
email = "kathrin.moellenhoff@rub.de")
as necessary.
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Check History
NOTE 12 OK · 2 NOTE · 0 WARNING · 0 ERROR · 0 FAILURE Mar 9, 2026
CRAN incoming feasibility
Maintainer: ‘Kathrin Moellenhoff <kathrin.moellenhoff@rub.de>’
No Authors@R field in DESCRIPTION.
Please add one, modifying
Authors@R: person(given = "Kathrin",
family = "Moellenhoff",
role = c("aut", "cre"),
email = "kathrin.moellenhoff@rub.de")
as necessary.
CRAN incoming feasibility
Maintainer: ‘Kathrin Moellenhoff <kathrin.moellenhoff@rub.de>’
No Authors@R field in DESCRIPTION.
Please add one, modifying
Authors@R: person(given = "Kathrin",
family = "Moellenhoff",
role = c("aut", "cre"),
email = "kathrin.moellenhoff@rub.de")
as necessary.