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SILGGM

Statistical Inference of Large-Scale Gaussian Graphical Model in Gene Networks

v1.0.0 · Oct 16, 2017 · GPL (>= 2)

Description

Provides a general framework to perform statistical inference of each gene pair and global inference of whole-scale gene pairs in gene networks using the well known Gaussian graphical model (GGM) in a time-efficient manner. We focus on the high-dimensional settings where p (the number of genes) is allowed to be far larger than n (the number of subjects). Four main approaches are supported in this package: (1) the bivariate nodewise scaled Lasso (Ren et al (2015) <doi:10.1214/14-AOS1286>) (2) the de-sparsified nodewise scaled Lasso (Jankova and van de Geer (2017) <doi:10.1007/s11749-016-0503-5>) (3) the de-sparsified graphical Lasso (Jankova and van de Geer (2015) <doi:10.1214/15-EJS1031>) (4) the GGM estimation with false discovery rate control (FDR) using scaled Lasso or Lasso (Liu (2013) <doi:10.1214/13-AOS1169>). Windows users should install 'Rtools' before the installation of this package.

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CRAN incoming feasibility

Maintainer: ‘Rong Zhang <roz16@pitt.edu>’

No Authors@R field in DESCRIPTION.
Please add one, modifying
  Authors@R: c(person(given = "Rong",
                      family = "Zhang",
                      role = c("aut", "cre"),
                      email = "roz16@pitt.edu"),
               person(given = "Zhao",
                      family = "Ren",
                      role = "aut"),
               person(given = "Wei",
                      family = "Chen",
                      role = "aut"))
as necessary.
NOTE r-devel-linux-x86_64-debian-gcc

CRAN incoming feasibility

Maintainer: ‘Rong Zhang <roz16@pitt.edu>’

No Authors@R field in DESCRIPTION.
Please add one, modifying
  Authors@R: c(person(given = "Rong",
                      family = "Zhang",
                      role = c("aut", "cre"),
                      email = "roz16@pitt.edu"),
               person(given = "Zhao",
                      family = "Ren",
                      role = "aut"),
               person(given = "Wei",
                      family = "Chen",
                      role = "aut"))
as necessary.
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Check History

NOTE 12 OK · 2 NOTE · 0 WARNING · 0 ERROR · 0 FAILURE Mar 9, 2026
NOTE r-devel-linux-x86_64-debian-clang

CRAN incoming feasibility

Maintainer: ‘Rong Zhang <roz16@pitt.edu>’

No Authors@R field in DESCRIPTION.
Please add one, modifying
  Authors@R: c(person(given = "Rong",
                      family = "Zhang",
                      role = c("aut", "cre"),
                      email = "roz16@pitt.edu"),
               person(given = "Zhao",
                      family = "Ren",
                      role = "aut"),
               person(given = "Wei",
                      family = "Chen",
                      role = "aut"
NOTE r-devel-linux-x86_64-debian-gcc

CRAN incoming feasibility

Maintainer: ‘Rong Zhang <roz16@pitt.edu>’

No Authors@R field in DESCRIPTION.
Please add one, modifying
  Authors@R: c(person(given = "Rong",
                      family = "Zhang",
                      role = c("aut", "cre"),
                      email = "roz16@pitt.edu"),
               person(given = "Zhao",
                      family = "Ren",
                      role = "aut"),
               person(given = "Wei",
                      family = "Chen",
                      role = "aut"

Dependency Network

Dependencies Reverse dependencies Rcpp glasso MASS reshape SILGGM

Version History

new 1.0.0 Mar 9, 2026