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POSTm

Phylogeny-Guided OTU-Specific Association Test for Microbiome Data

v1.4 · Apr 17, 2024 · GPL-2

Description

Implements the Phylogeny-Guided Microbiome OTU-Specific Association Test method, which boosts the testing power by adaptively borrowing information from phylogenetically close OTUs (operational taxonomic units) of the target OTU. This method is built on a kernel machine regression framework and allows for flexible modeling of complex microbiome effects, adjustments for covariates, and can accommodate both continuous and binary outcomes.

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OK 14 OK · 0 NOTE · 0 WARNING · 0 ERROR · 0 FAILURE Mar 9, 2026

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Dependencies Reverse dependencies CompQuadForm ape POSTm

Version History

new 1.4 Mar 9, 2026