MultisiteMediation
Causal Mediation Analysis in Multisite Trials
Description
Multisite causal mediation analysis using the methods proposed by Qin and Hong (2017) <doi:10.3102/1076998617694879>, Qin, Hong, Deutsch, and Bein (2019) <doi:10.1111/rssa.12446>, and Qin, Deutsch, and Hong (2021) <doi:10.1002/pam.22268>. It enables causal mediation analysis in multisite trials, in which individuals are assigned to a treatment or a control group at each site. It allows for estimation and hypothesis testing for not only the population average but also the between-site variance of direct and indirect effects transmitted through one single mediator or two concurrent (conditionally independent) mediators. This strategy conveniently relaxes the assumption of no treatment-by-mediator interaction while greatly simplifying the outcome model specification without invoking strong distributional assumptions. This package also provides a function that can further incorporate a sample weight and a nonresponse weight for multisite causal mediation analysis in the presence of complex sample and survey designs and non-random nonresponse, to enhance both the internal validity and external validity. The package also provides a weighting-based balance checking function for assessing the remaining overt bias.
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CRAN Check Status
Show all 14 flavors
| Flavor | Status |
|---|---|
| r-devel-linux-x86_64-debian-clang | NOTE |
| r-devel-linux-x86_64-debian-gcc | NOTE |
| r-devel-linux-x86_64-fedora-clang | OK |
| r-devel-linux-x86_64-fedora-gcc | OK |
| r-devel-macos-arm64 | OK |
| r-devel-windows-x86_64 | OK |
| r-oldrel-macos-arm64 | OK |
| r-oldrel-macos-x86_64 | OK |
| r-oldrel-windows-x86_64 | OK |
| r-patched-linux-x86_64 | OK |
| r-release-linux-x86_64 | OK |
| r-release-macos-arm64 | OK |
| r-release-macos-x86_64 | OK |
| r-release-windows-x86_64 | OK |
Check details (14 non-OK)
CRAN incoming feasibility
Maintainer: ‘Xu Qin <xuqin@pitt.edu>’
No Authors@R field in DESCRIPTION.
Please add one, modifying
Authors@R: c(person(given = "Xu",
family = "Qin",
role = c("aut", "cre"),
email = "xuqin@pitt.edu"),
person(given = "Guanglei",
family = "Hong",
role = "aut"),
person(given = "Jonah",
family = "Deutsch",
role = "aut"),
person(given = "Edward",
family = "Bein",
role = "aut"))
as necessary.
CRAN incoming feasibility
Maintainer: ‘Xu Qin <xuqin@pitt.edu>’
No Authors@R field in DESCRIPTION.
Please add one, modifying
Authors@R: c(person(given = "Xu",
family = "Qin",
role = c("aut", "cre"),
email = "xuqin@pitt.edu"),
person(given = "Guanglei",
family = "Hong",
role = "aut"),
person(given = "Jonah",
family = "Deutsch",
role = "aut"),
person(given = "Edward",
family = "Bein",
role = "aut"))
as necessary.
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Check History
NOTE 12 OK · 2 NOTE · 0 WARNING · 0 ERROR · 0 FAILURE Mar 9, 2026
CRAN incoming feasibility
Maintainer: ‘Xu Qin <xuqin@pitt.edu>’
No Authors@R field in DESCRIPTION.
Please add one, modifying
Authors@R: c(person(given = "Xu",
family = "Qin",
role = c("aut", "cre"),
email = "xuqin@pitt.edu"),
person(given = "Guanglei",
family = "Hong",
role = "aut"),
person(given = "Jonah",
family = "Deutsch",
role = "au
CRAN incoming feasibility
Maintainer: ‘Xu Qin <xuqin@pitt.edu>’
No Authors@R field in DESCRIPTION.
Please add one, modifying
Authors@R: c(person(given = "Xu",
family = "Qin",
role = c("aut", "cre"),
email = "xuqin@pitt.edu"),
person(given = "Guanglei",
family = "Hong",
role = "aut"),
person(given = "Jonah",
family = "Deutsch",
role = "au