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MLML2R

Maximum Likelihood Estimation of DNA Methylation and Hydroxymethylation Proportions

v0.3.3 · Oct 17, 2019 · MIT + file LICENSE
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Description

Maximum likelihood estimates (MLE) of the proportions of 5-mC and 5-hmC in the DNA using information from BS-conversion, TAB-conversion, and oxBS-conversion methods. One can use information from all three methods or any combination of two of them. Estimates are based on Binomial model by Qu et al. (2013) <doi:10.1093/bioinformatics/btt459> and Kiihl et al. (2019) <doi:10.1515/sagmb-2018-0031>.

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Maintainer: ‘Samara Kiihl <samara@ime.unicamp.br>’

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  Authors@R: c(person(given = "Samara",
                      family = "Kiihl",
                      role = c("aut", "cre"),
                      email = "samara@ime.unicamp.br"),
               person(given = c("Maria", "Jose"),
                      family = "Martinez-Garrido",
                      role = "aut"),
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                      family = "Domingo-Relloso",
                      role = "aut"),
               person(given = "Jose",
                      family = "Bermudez",
                      role = "aut"),
               person(given = "Maria",
                      family = "Tellez-Plaza",
                      role = "aut"))
as necessary.

Package CITATION file contains call(s) to old-style personList() or
as.personList().  Please use c() on person objects instead.
Package CITATION file contains call(s) to old-style citEntry().  Please
use bibentry() instead.
NOTE r-devel-linux-x86_64-debian-gcc

CRAN incoming feasibility

Maintainer: ‘Samara Kiihl <samara@ime.unicamp.br>’

No Authors@R field in DESCRIPTION.
Please add one, modifying
  Authors@R: c(person(given = "Samara",
                      family = "Kiihl",
                      role = c("aut", "cre"),
                      email = "samara@ime.unicamp.br"),
               person(given = c("Maria", "Jose"),
                      family = "Martinez-Garrido",
                      role = "aut"),
               person(given = "Arce",
                      family = "Domingo-Relloso",
                      role = "aut"),
               person(given = "Jose",
                      family = "Bermudez",
                      role = "aut"),
               person(given = "Maria",
                      family = "Tellez-Plaza",
                      role = "aut"))
as necessary.

Package CITATION file contains call(s) to old-style personList() or
as.personList().  Please use c() on person objects instead.
Package CITATION file contains call(s) to old-style citEntry().  Please
use bibentry() instead.
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CRAN incoming feasibility

                
Maintainer: ‘Samara Kiihl <samara@ime.unicamp.br>’

No Authors@R field in DESCRIPTION.
Please add one, modifying
  Authors@R: c(person(given = "Samara",
                      family = "Kiihl",
                      role = c("aut", "cre"),
                      email = "samara@ime.unicamp.br"),
               person(given = c("Maria", "Jose"),
                      family = "Martinez-Garrido",
                      role = "aut"),
               person(given = "Arce",
                      family 

              

              

                

                  NOTE
                  r-devel-linux-x86_64-debian-gcc
                

                
CRAN incoming feasibility

                
Maintainer: ‘Samara Kiihl <samara@ime.unicamp.br>’

No Authors@R field in DESCRIPTION.
Please add one, modifying
  Authors@R: c(person(given = "Samara",
                      family = "Kiihl",
                      role = c("aut", "cre"),
                      email = "samara@ime.unicamp.br"),
               person(given = c("Maria", "Jose"),
                      family = "Martinez-Garrido",
                      role = "aut"),
               person(given = "Arce",
                      family 

              

              

                

                  NOTE
                  r-oldrel-macos-arm64
                

                
package dependencies

                
Package suggested but not available for checking: ‘IlluminaHumanMethylation450kmanifest’

              

              

                

                  NOTE
                  r-oldrel-macos-x86_64
                

                
package dependencies

                
Package suggested but not available for checking: ‘IlluminaHumanMethylation450kmanifest’

              

            

          

        

      


      

      

      
      

        
Version History

        

          

            new
            0.3.3
            Mar 10, 2026