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HiCociety

Inferring Chromatin Interaction Modules from 3C-Based Data

v0.1.39 · Feb 16, 2026 · GPL-3

Description

Identifies chromatin interaction modules by constructing a Hi-C contact network based on statistically significant interactions, followed by network clustering. The method enables comparison of module connectivity across two Hi-C datasets and is capable of detecting cell-type-specific regulatory modules. By integrating network analysis with chromatin conformation data, this approach provides insights into the spatial organization of the genome and its functional implications in gene regulation. Author: Sora Yoon (2025) <https://github.com/ysora/HiCociety>.

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CRAN Check Status

5 ERROR
1 NOTE
8 OK
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r-devel-linux-x86_64-debian-clang ERROR
r-devel-linux-x86_64-debian-gcc OK
r-devel-linux-x86_64-fedora-clang OK
r-devel-linux-x86_64-fedora-gcc OK
r-devel-macos-arm64 OK
r-devel-windows-x86_64 OK
r-oldrel-macos-arm64 ERROR
r-oldrel-macos-x86_64 ERROR
r-oldrel-windows-x86_64 NOTE
r-patched-linux-x86_64 OK
r-release-linux-x86_64 OK
r-release-macos-arm64 ERROR
r-release-macos-x86_64 ERROR
r-release-windows-x86_64 OK
Check details (18 non-OK)
ERROR r-devel-linux-x86_64-debian-clang

package dependencies

Packages required but not available: 'AnnotationDbi', 'GenomicFeatures'

Packages suggested but not available for checking:
  'biomaRt', 'TxDb.Hsapiens.UCSC.hg38.knownGene',
  'TxDb.Mmusculus.UCSC.mm10.knownGene', 'org.Mm.eg.db', 'org.Hs.eg.db'

See section ‘The DESCRIPTION file’ in the ‘Writing R Extensions’
manual.
OK r-devel-linux-x86_64-debian-gcc

*


            
OK r-devel-linux-x86_64-fedora-clang

*


            
OK r-devel-linux-x86_64-fedora-gcc

*


            
OK r-devel-macos-arm64

*


            
OK r-devel-windows-x86_64

*


            
ERROR r-oldrel-macos-arm64

examples

Running examples in ‘HiCociety-Ex.R’ failed
The error most likely occurred in:

> ### Name: add_Genes
> ### Title: Add gene information
> ### Aliases: add_Genes
> 
> ### ** Examples
> 
> modulefile = system.file('extdata','mouse_naiveCD4T_Vahedi_short.rds',
+ package = 'HiCocietyExample')
> mycom = readRDS(modulefile)
> mycom$ModuleSummary = add_Genes(mycom$ModuleSummary,
+ 'TxDb.Mmusculus.UCSC.mm10.knownGene')
Error in add_Genes(mycom$ModuleSummary, "TxDb.Mmusculus.UCSC.mm10.knownGene") : 
  Package TxDb.Mmusculus.UCSC.mm10.knownGene not found
Execution halted
NOTE r-oldrel-macos-arm64

installed package size

  installed size is  6.6Mb
NOTE r-oldrel-macos-arm64

package dependencies

Packages suggested but not available for checking:
  'TxDb.Hsapiens.UCSC.hg38.knownGene',
  'TxDb.Mmusculus.UCSC.mm10.knownGene', 'org.Mm.eg.db'
ERROR r-oldrel-macos-x86_64

examples

Running examples in ‘HiCociety-Ex.R’ failed
The error most likely occurred in:

> ### Name: add_Genes
> ### Title: Add gene information
> ### Aliases: add_Genes
> 
> ### ** Examples
> 
> modulefile = system.file('extdata','mouse_naiveCD4T_Vahedi_short.rds',
+ package = 'HiCocietyExample')
> mycom = readRDS(modulefile)
> mycom$ModuleSummary = add_Genes(mycom$ModuleSummary,
+ 'TxDb.Mmusculus.UCSC.mm10.knownGene')
Error in add_Genes(mycom$ModuleSummary, "TxDb.Mmusculus.UCSC.mm10.knownGene") : 
  Package TxDb.Mmusculus.UCSC.mm10.knownGene not found
Execution halted
NOTE r-oldrel-macos-x86_64

installed package size

  installed size is  6.6Mb
NOTE r-oldrel-macos-x86_64

package dependencies

Packages suggested but not available for checking:
  'TxDb.Hsapiens.UCSC.hg38.knownGene',
  'TxDb.Mmusculus.UCSC.mm10.knownGene'
NOTE r-oldrel-windows-x86_64

installed package size

  installed size is  6.8Mb
OK r-patched-linux-x86_64

*


            
OK r-release-linux-x86_64

*


            
ERROR r-release-macos-arm64

examples

Running examples in ‘HiCociety-Ex.R’ failed
The error most likely occurred in:

> ### Name: add_Genes
> ### Title: Add gene information
> ### Aliases: add_Genes
> 
> ### ** Examples
> 
> modulefile = system.file('extdata','mouse_naiveCD4T_Vahedi_short.rds',
+ package = 'HiCocietyExample')
> mycom = readRDS(modulefile)
> mycom$ModuleSummary = add_Genes(mycom$ModuleSummary,
+ 'TxDb.Mmusculus.UCSC.mm10.knownGene')
Error in add_Genes(mycom$ModuleSummary, "TxDb.Mmusculus.UCSC.mm10.knownGene") : 
  Package TxDb.Mmusculus.UCSC.mm10.knownGene not found
Execution halted
ERROR r-release-macos-x86_64

examples

Running examples in ‘HiCociety-Ex.R’ failed
The error most likely occurred in:

> ### Name: add_Genes
> ### Title: Add gene information
> ### Aliases: add_Genes
> 
> ### ** Examples
> 
> modulefile = system.file('extdata','mouse_naiveCD4T_Vahedi_short.rds',
+ package = 'HiCocietyExample')
> mycom = readRDS(modulefile)
> mycom$ModuleSummary = add_Genes(mycom$ModuleSummary,
+ 'TxDb.Mmusculus.UCSC.mm10.knownGene')
Error in add_Genes(mycom$ModuleSummary, "TxDb.Mmusculus.UCSC.mm10.knownGene") : 
  Package TxDb.Mmusculus.UCSC.mm10.knownGene not found
Execution halted
OK r-release-windows-x86_64

*


            

Additional Issues

noSuggests Details →

Check History

ERROR 8 OK · 1 NOTE · 0 WARNING · 5 ERROR · 0 FAILURE Mar 9, 2026
ERROR r-devel-linux-x86_64-debian-clang

package dependencies

Packages required but not available: 'AnnotationDbi', 'GenomicFeatures'

Packages suggested but not available for checking:
  'biomaRt', 'TxDb.Hsapiens.UCSC.hg38.knownGene',
  'TxDb.Mmusculus.UCSC.mm10.knownGene', 'org.Mm.eg.db', 'org.Hs.eg.db'

See section ‘The DESCRIPTION file’ in the ‘Writing R Extensions’
manual.
ERROR r-release-macos-arm64

examples

Running examples in ‘HiCociety-Ex.R’ failed
The error most likely occurred in:

> ### Name: add_Genes
> ### Title: Add gene information
> ### Aliases: add_Genes
> 
> ### ** Examples
> 
> modulefile = system.file('extdata','mouse_naiveCD4T_Vahedi_short.rds',
+ package = 'HiCocietyExample')
> mycom = readRDS(modulefile)
> mycom$ModuleSummary = add_Genes(mycom$ModuleSummary,
+ 'TxDb.Mmusculus.UCSC.mm10.knownGene')
Error in add_Genes(mycom$ModuleSummary, "TxDb.Mmusculus.UCSC.mm10.knownGene") : 
  Pa
ERROR r-release-macos-x86_64

examples

Running examples in ‘HiCociety-Ex.R’ failed
The error most likely occurred in:

> ### Name: add_Genes
> ### Title: Add gene information
> ### Aliases: add_Genes
> 
> ### ** Examples
> 
> modulefile = system.file('extdata','mouse_naiveCD4T_Vahedi_short.rds',
+ package = 'HiCocietyExample')
> mycom = readRDS(modulefile)
> mycom$ModuleSummary = add_Genes(mycom$ModuleSummary,
+ 'TxDb.Mmusculus.UCSC.mm10.knownGene')
Error in add_Genes(mycom$ModuleSummary, "TxDb.Mmusculus.UCSC.mm10.knownGene") : 
  Pa
ERROR r-oldrel-macos-arm64

package dependencies

Packages suggested but not available for checking:
  'TxDb.Hsapiens.UCSC.hg38.knownGene',
  'TxDb.Mmusculus.UCSC.mm10.knownGene', 'org.Mm.eg.db'
ERROR r-oldrel-macos-x86_64

package dependencies

Packages suggested but not available for checking:
  'TxDb.Hsapiens.UCSC.hg38.knownGene',
  'TxDb.Mmusculus.UCSC.mm10.knownGene'
NOTE r-oldrel-windows-x86_64

installed package size

  installed size is  6.8Mb

Dependency Network

Dependencies Reverse dependencies strawr shape fitdistrplus igraph foreach doParallel Rcpp AnnotationDbi GenomicFeatures IRanges S4Vectors GenomicRanges pracma signal HiCocietyExample HiCociety

Version History

new 0.1.39 Mar 9, 2026