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GencoDymo2

Comprehensive Analysis of 'GENCODE' Annotations and Splice Site Motifs

v1.0.4 · Jan 12, 2026 · GPL (>= 3)

Description

A comprehensive suite of helper functions designed to facilitate the analysis of genomic annotations from the 'GENCODE' database <https://www.gencodegenes.org/>, supporting both human and mouse genomes. This toolkit enables users to extract, filter, and analyze a wide range of annotation features including genes, transcripts, exons, and introns across different 'GENCODE' releases. It provides functionality for cross-version comparisons, allowing researchers to systematically track annotation updates, structural changes, and feature-level differences between releases. In addition, the package can generate high-quality FASTA files containing donor and acceptor splice site motifs, which are formatted for direct input into the 'MaxEntScan' tool (Yeo and Burge, 2004 <doi:10.1089/1066527041410418>), enabling accurate calculation of splice site strength scores.

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CRAN Check Status

1 ERROR
1 NOTE
12 OK
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r-devel-linux-x86_64-debian-clang OK
r-devel-linux-x86_64-debian-gcc OK
r-devel-linux-x86_64-fedora-clang OK
r-devel-linux-x86_64-fedora-gcc OK
r-devel-macos-arm64 OK
r-devel-windows-x86_64 OK
r-oldrel-macos-arm64 NOTE
r-oldrel-macos-x86_64 ERROR
r-oldrel-windows-x86_64 OK
r-patched-linux-x86_64 OK
r-release-linux-x86_64 OK
r-release-macos-arm64 OK
r-release-macos-x86_64 OK
r-release-windows-x86_64 OK
Check details (2 non-OK)
NOTE r-oldrel-macos-arm64

package dependencies

Package suggested but not available for checking: ‘BSgenome.Hsapiens.UCSC.hg38’
ERROR r-oldrel-macos-x86_64

package dependencies

Packages required and available but unsuitable versions:
  'Biostrings', 'GenomicRanges', 'rtracklayer', 'IRanges'

Package suggested but not available for checking: ‘BSgenome.Hsapiens.UCSC.hg38’

See section ‘The DESCRIPTION file’ in the ‘Writing R Extensions’
manual.

Check History

ERROR 12 OK · 1 NOTE · 0 WARNING · 1 ERROR · 0 FAILURE Mar 10, 2026
NOTE r-oldrel-macos-arm64

package dependencies

Package suggested but not available for checking: ‘BSgenome.Hsapiens.UCSC.hg38’
ERROR r-oldrel-macos-x86_64

package dependencies

Packages required and available but unsuitable versions:
  'Biostrings', 'GenomicRanges', 'rtracklayer', 'IRanges'

Package suggested but not available for checking: ‘BSgenome.Hsapiens.UCSC.hg38’

See section ‘The DESCRIPTION file’ in the ‘Writing R Extensions’
manual.

Dependency Network

Dependencies Reverse dependencies Biostrings BSgenome data.table (>= 1.17.0) dplyr GenomicRanges plotrix progress RCurl (>= 1.98.1.17) rtracklayer tidyr IRanges GencoDymo2

Version History

new 1.0.4 Mar 10, 2026
updated 1.0.4 ← 1.0.3 diff Jan 11, 2026
updated 1.0.3 ← 1.0.2 diff Aug 20, 2025
updated 1.0.2 ← 1.0.1 diff Jul 13, 2025
new 1.0.1 May 14, 2025