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DIscBIO

A User-Friendly Pipeline for Biomarker Discovery in Single-Cell Transcriptomics

v1.2.3 · Jan 8, 2026 · MIT + file LICENSE

Description

An open, multi-algorithmic pipeline for easy, fast and efficient analysis of cellular sub-populations and the molecular signatures that characterize them. The pipeline consists of four successive steps: data pre-processing, cellular clustering with pseudo-temporal ordering, defining differential expressed genes and biomarker identification. More details on Ghannoum et. al. (2021) <doi:10.3390/ijms22031399>. This package implements extensions of the work published by Ghannoum et. al. (2019) <doi:10.1101/700989>.

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CRAN Check Status

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r-devel-linux-x86_64-debian-clang ERROR
r-devel-linux-x86_64-debian-gcc OK
r-devel-linux-x86_64-fedora-clang OK
r-devel-linux-x86_64-fedora-gcc OK
r-devel-macos-arm64 OK
r-devel-windows-x86_64 OK
r-oldrel-macos-arm64 ERROR
r-oldrel-macos-x86_64 OK
r-oldrel-windows-x86_64 ERROR
r-patched-linux-x86_64 OK
r-release-linux-x86_64 OK
r-release-macos-arm64 ERROR
r-release-macos-x86_64 ERROR
r-release-windows-x86_64 OK
Check details (14 non-OK)
ERROR r-devel-linux-x86_64-debian-clang

package dependencies

Packages required but not available:
  'SingleCellExperiment', 'TSCAN', 'RWeka'

Packages suggested but not available for checking:
  'org.Hs.eg.db', 'AnnotationDbi'

See section ‘The DESCRIPTION file’ in the ‘Writing R Extensions’
manual.
OK r-devel-linux-x86_64-debian-gcc

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OK r-devel-linux-x86_64-fedora-clang

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OK r-devel-linux-x86_64-fedora-gcc

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OK r-devel-macos-arm64

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OK r-devel-windows-x86_64

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ERROR r-oldrel-macos-arm64

package dependencies

Package required but not available: ‘TSCAN’

See section ‘The DESCRIPTION file’ in the ‘Writing R Extensions’
manual.
OK r-oldrel-macos-x86_64

*


            
ERROR r-oldrel-windows-x86_64

whether package can be installed

Installation failed.
See 'd:/Rcompile/CRANpkg/local/4.4/DIscBIO.Rcheck/00install.out' for details.
OK r-patched-linux-x86_64

*


            
OK r-release-linux-x86_64

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ERROR r-release-macos-arm64

package dependencies

Package required but not available: ‘TSCAN’

See section ‘The DESCRIPTION file’ in the ‘Writing R Extensions’
manual.
ERROR r-release-macos-x86_64

package dependencies

Package required but not available: ‘TSCAN’

See section ‘The DESCRIPTION file’ in the ‘Writing R Extensions’
manual.
OK r-release-windows-x86_64

*


            

Check History

ERROR 9 OK · 0 NOTE · 0 WARNING · 5 ERROR · 0 FAILURE Mar 9, 2026
ERROR r-devel-linux-x86_64-debian-clang

package dependencies

Packages required but not available:
  'SingleCellExperiment', 'TSCAN', 'RWeka'

Packages suggested but not available for checking:
  'org.Hs.eg.db', 'AnnotationDbi'

See section ‘The DESCRIPTION file’ in the ‘Writing R Extensions’
manual.
ERROR r-release-macos-arm64

package dependencies

Package required but not available: ‘TSCAN’

See section ‘The DESCRIPTION file’ in the ‘Writing R Extensions’
manual.
ERROR r-release-macos-x86_64

package dependencies

Package required but not available: ‘TSCAN’

See section ‘The DESCRIPTION file’ in the ‘Writing R Extensions’
manual.
ERROR r-oldrel-macos-arm64

package dependencies

Package required but not available: ‘TSCAN’

See section ‘The DESCRIPTION file’ in the ‘Writing R Extensions’
manual.
ERROR r-oldrel-windows-x86_64

whether package can be installed

Installation failed.
See 'd:/Rcompile/CRANpkg/local/4.4/DIscBIO.Rcheck/00install.out' for details.

Dependency Network

Dependencies Reverse dependencies SingleCellExperiment TSCAN httr mclust statmod igraph RWeka vegan NetIndices png RColorBrewer ggplot2 rpart fpc cluster +4 more dependencies DIscBIO

Version History

new 1.2.3 Mar 9, 2026